Uninducible lexA mutant response to ciprofloxacin: time course
Summary:
Analysis of Pseudomonas aeruginosa mutant bearing an uninducible lexA repressor at various time points after treatment with the antibiotic ciprofloxacin. LexA negatively regulates SOS genes. Results provide insight into the role of the SOS pathway in the response to ciprofloxacin.
Cirz RT, O'Neill BM, Hammond JA, Head SR et al. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. J Bacteriol 2006 Oct;188(20):7101-10. PMID: 17015649
