Spermatogonial stem cell self-renewal: time course
Summary:
Analysis of spermatogonial stem cells (SSCs) at various time points following withdrawal and replacement of glial cell line-derived neurotrophic factor (GDNF) and GDNF-family receptor alpha-1 (GFRalpha1). Results provide insight into the mechanisms of GDNF-supported in vitro self-renewal of SSCs.
Oatley JM, Avarbock MR, Telaranta AI, Fearon DT et al. Identifying genes important for spermatogonial stem cell self-renewal and survival. Proc Natl Acad Sci U S A 2006 Jun 20;103(25):9524-9. PMID: 16740658