Muscle cell survival mediated by transcriptional coactivator p300
Summary:
Analysis of insulin growth factor II deficient C2AS12 myoblasts expressing wild type or protein interaction domain mutant p300 at 0 and 24 hours after a switch to low serum media. Wild type but not the mutant p300 prevents the progressive cell death induced by serum withdrawal.
GPL81:
[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array
Citation:
Kuninger D, Wright A, Rotwein P. Muscle cell survival mediated by the transcriptional coactivators p300 and PCAF displays different requirements for acetyltransferase activity. Am J Physiol Cell Physiol 2006 Oct;291(4):C699-709. PMID: 16672693
