C57/B6 mice subjected either to sham laparotomy or cecal ligation and puncture (CLP) and spleen samples taken 24 hours post surgery. Effort to increase understanding of shock and the adaptive response to injury at the level of the entire genome.
Cobb JP, Laramie JM, Stormo GD, Morrissey JJ et al. Sepsis gene expression profiling: murine splenic compared with hepatic responses determined by using complementary DNA microarrays. Crit Care Med 2002 Dec;30(12):2711-21. PMID: 12483063
