Analysis of Caco-2 intestinal epithelial cells cocultured for 6 hours with the probiotic Escherichia coli strain Nissle 1917 (EcN). A controlled clinical trial suggests that EcN is effective in remission maintenance of ulcerative colitis. Results provide insight into EcN-host interactions.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Ukena SN, Westendorf AM, Hansen W, Rohde M et al. The host response to the probiotic Escherichia coli strain Nissle 1917: specific up-regulation of the proinflammatory chemokine MCP-1. BMC Med Genet 2005 Dec 13;6:43. PMID: 16351713