Comparison of mesenchymal stem cells (MSC) treated with dimethylsulphoxide and butylated hydroxyanisole (DMSO/BHA) for 6 or 48 hours to fetal brain (positive control) or adult liver (negative control). Results raise doubts about the DMSO/BHA protocol for generating neural cells from MSCs.
GPL2136:
Micro-CRIBI Human Oligo Array (Operon V2.0)
Citation:
Bertani N, Malatesta P, Volpi G, Sonego P et al. Neurogenic potential of human mesenchymal stem cells revisited: analysis by immunostaining, time-lapse video and microarray. J Cell Sci 2005 Sep 1;118(Pt 17):3925-36. PMID: 16091422