Barrett's metaplasia progression to adenocarcinoma
Summary:
Expression profiling of normal esophageal epithelium, premalignant Barrett's metaplasia, and esophageal adenocarcinoma samples. Tissue samples of each type obtained from 8 patients by transhiatal esophagectomy. Results identify potential markers of disease progression.
GPL96:
[HG-U133A] Affymetrix Human Genome U133A Array
Citation:
Kimchi ET, Posner MC, Park JO, Darga TE et al. Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation. Cancer Res 2005 Apr 15;65(8):3146-54. PMID: 15833844
