Estrogen receptor alpha/beta heterodimer action in response to estrogen and tamoxifen
Summary:
Expression profiling of U2OS osteosarcoma cell line expressing estrogen receptor/alpha heterodimer after treatment with 10 nM 17beta-estradiol (E2) or 10 nM 4-OH tamoxifen (4HT) for 24 hours. Results provide insight into the role of estrogen receptor/alpha heterodimer in gene regulation.
GPL201:
[HG-Focus] Affymetrix Human HG-Focus Target Array
Citation:
Monroe DG, Secreto FJ, Subramaniam M, Getz BJ et al. Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells. Mol Endocrinol 2005 Jun;19(6):1555-68. PMID: 15802376
