Adenylate cyclase activator forskolin effect on pheochromocytoma cell line (RAE230B)
Summary:
Expression profiling of PC12 pheochromocytoma cells treated with 10 uM forskolin for 1 hour. Forskolin activates adenylate cyclase. Effect of 1,9 dideoxy forskolin, an inactive analog of forskolin, also examined. Results identify genes whose expression responds to changes in cAMP levels.
GPL342:
[RAE230B] Affymetrix Rat Expression 230B Array
Citation:
Impey S, McCorkle SR, Cha-Molstad H, Dwyer JM et al. Defining the CREB regulon: a genome-wide analysis of transcription factor regulatory regions. Cell 2004 Dec 29;119(7):1041-54. PMID: 15620361
