Webs Services

COG

1. Get all COGs:
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?format=json
2. Filter COGs by gene tag: MK0280
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?gene=MK0280
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?gene=MK0280&format=json
3. Filter COGs by COG ID tag: COG0003
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cog=COG0003
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cog=COG0003&format=json
4. Filter COGs by assembly ID: GCA_000007185.1
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?assembly=GCA_000007185.1
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?assembly=GCA_000007185.1&format=json
5. Filter COGs by organism name: Nitrosopumilus_maritimus_SCM1
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?organism=Nitrosopumilus_maritimus_SCM1
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?organism=Nitrosopumilus_maritimus_SCM11&format=json
6. Filter COGs by taxid: 1229908
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?taxid=1229908
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?taxid=1229908&format=json
7. Filter COGs by Taxonomic Category: ACTINOBACTERIA
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?category=ACTINOBACTERIA
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?category=ACTINOBACTERIA&format=json
8. Filter COGs by Taxonomic Category taxid: 651137
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cat_taxid=651137
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cat_taxid=651137&format=json
9. Filter COGs by Protein name: AJP49128.1
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?protein=AJP49128.1
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?protein=AJP49128.1&format=json

COG combined queries

The search keywords (cog, assembly, organism, taxid, category, cat_taxid and protein) can be combined to filter the COG lists.

1. Filter COGs by COG id and Taxonomy Categories: COG0004 and CYANOBACTERIA
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cog=COG0004&category=CYANOBACTERIA
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cog=COG0004&category=CYANOBACTERIA&format=json
2. Filter COGs by COG id and organism: COG0004 and Escherichia_coli_K-12_sub_MG1655
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cog=COG0004&organism=Escherichia_coli_K-12_sub_MG1655
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cog/?cog=COG0004&organism=Escherichia_coli_K-12_sub_MG1655&format=json

COG Definitions

1. Get all COG Definitions:
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cogdef/
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cogdef/?format=json
2. Get specific COG Definitions by COG: COG0003
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cogdef/?cog=COG0003
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cogdef/?cog=COG0003&format=json
3. Get specific COG Definitions by name: Thiamin-binding stress-response protein YqgV, UPF0045 family
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/cogdef/?name=Thiamin-binding%20stress-response%20protein%20YqgV,%20UPF0045%20family
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/cogdef/?name=Thiamin-binding%20stress-response%20protein%20YqgV,%20UPF0045%20family&format=json

Taxonomic Categories

1. Get all Taxonomic Categories:
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/taxonomy/
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/taxonomy/?format=json
2. Get specific Taxonomic Category by name: ALPHAPROTEOBACTERIA
   Web API: https://ncbi.nlm.nih.gov/research/cog/api/taxonomy/?name=ALPHAPROTEOBACTERIA
   JSON Format: https://ncbi.nlm.nih.gov/research/cog/api/taxonomy/?name=ALPHAPROTEOBACTERIA&format=json