Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1965 1
1969 1
1975 1
1976 2
1980 1
1991 1
1992 1
1993 1
1994 3
1995 2
1996 8
1997 5
1998 3
2000 3
2001 4
2002 3
2003 4
2004 4
2005 8
2006 12
2007 10
2008 10
2009 2
2010 4
2011 6
2012 8
2013 9
2014 6
2015 16
2016 12
2017 11
2018 16
2019 14
2020 8
2021 12
2022 14
2023 15
2024 3

Text availability

Article attribute

Article type

Publication date

Search Results

219 results

Results by year

Filters applied: . Clear all
Page 1
Coriolus versicolor polysaccharopeptide as an immunotherapeutic in China.
Dou H, Chang Y, Zhang L. Dou H, et al. Prog Mol Biol Transl Sci. 2019;163:361-381. doi: 10.1016/bs.pmbts.2019.03.001. Epub 2019 Apr 1. Prog Mol Biol Transl Sci. 2019. PMID: 31030754 Review.
Coriolus versicoloris is one of the well-known traditional medicinal mushrooms used in China for over 2000 years. Polysaccharopeptide (PSP) is identified as the major bioactive component, which can be obtained from the mycelium or fermentation broth of Coriolus versicolor. …
Coriolus versicoloris is one of the well-known traditional medicinal mushrooms used in China for over 2000 years. Polysaccharopeptide …
Immunomodulatory Properties of Coriolus versicolor: The Role of Polysaccharopeptide.
Saleh MH, Rashedi I, Keating A. Saleh MH, et al. Front Immunol. 2017 Sep 6;8:1087. doi: 10.3389/fimmu.2017.01087. eCollection 2017. Front Immunol. 2017. PMID: 28932226 Free PMC article. Review.
We report on the induction of a largely pro-inflammatory cytokine profile by the polysaccharopeptide (PSP) isolated from the Coriolus versicolor (Yun zhi) mushroom, as well as its effects on various immune subsets, and the clinical data that have led to its widespread adop …
We report on the induction of a largely pro-inflammatory cytokine profile by the polysaccharopeptide (PSP) isolated from the Coriolus …
Preclinical and clinical studies of Coriolus versicolor polysaccharopeptide as an immunotherapeutic in China.
Chang Y, Zhang M, Jiang Y, Liu Y, Luo H, Hao C, Zeng P, Zhang L. Chang Y, et al. Discov Med. 2017 Apr;23(127):207-219. Discov Med. 2017. PMID: 28595034 Free article. Review.
Interestingly, an immunotherapeutic regime that employs polysaccharopeptide (PSP), a unique peptide-containing polysaccharide isolated from Coriolus versicolor, has already become a routine clinical practice in Japan since 1977 and in China since 1987. ...
Interestingly, an immunotherapeutic regime that employs polysaccharopeptide (PSP), a unique peptide-containing polysaccharide isolate …
Polysaccharopeptide exerts immunoregulatory effects via MyD88-dependent signaling pathway.
Feng Z, Wang Z, Yang M, Zhou L, Bao Y. Feng Z, et al. Int J Biol Macromol. 2016 Jan;82:201-7. doi: 10.1016/j.ijbiomac.2015.11.002. Epub 2015 Nov 4. Int J Biol Macromol. 2016. PMID: 26546866
AIMS: The present study is to investigate the immunomodulatory mechanism and related pathways of polysaccharopeptide (PSP) in mice bearing Ehrlich's ascites carcinoma (EAC). ...
AIMS: The present study is to investigate the immunomodulatory mechanism and related pathways of polysaccharopeptide (PSP) in mice be …
Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK.
Liu J, Lau EY, Chen J, Yong J, Tang KD, Lo J, Ng IO, Lee TK, Ling MT. Liu J, et al. BMC Complement Altern Med. 2014 Aug 16;14:303. doi: 10.1186/1472-6882-14-303. BMC Complement Altern Med. 2014. PMID: 25129068 Free PMC article.
METHOD: We recently reported that the two natural compounds polysaccharopeptide (PSP) and Gamma-tocotrienols (gamma-T3) possessed potent anti-cancer activities through targeting of CSCs. ...
METHOD: We recently reported that the two natural compounds polysaccharopeptide (PSP) and Gamma-tocotrienols (gamma-T3) possessed pot …
Recent Advances and Challenges in Studies of Control of Cancer Stem Cells and the Gut Microbiome by the Trametes-Derived Polysaccharopeptide PSP (Review).
Wu JM, Doonan BB, Hsieh TC, Yang Q, Yang XT, Ling MT. Wu JM, et al. Int J Med Mushrooms. 2016;18(8):651-660. doi: 10.1615/IntJMedMushrooms.v18.i8.10. Int J Med Mushrooms. 2016. PMID: 27910783 Review.
The reported health benefits of T. versicolor led to a search for the identity of its bioactive ingredients. These efforts have resulted in the isolation of the polysaccharopeptide PSP from cultured mycelia of strain Cov-1, which expresses large amounts of PSP. ...
The reported health benefits of T. versicolor led to a search for the identity of its bioactive ingredients. These efforts have resulted in …
Polysaccharopeptide enhances the anticancer activity of doxorubicin and etoposide on human breast cancer cells ZR-75-30.
Wan JM, Sit WH, Louie JC. Wan JM, et al. Int J Oncol. 2008 Mar;32(3):689-99. Int J Oncol. 2008. PMID: 18292947
In search of natural bioactive microbial compounds with adjuvant properties, we have previously showed that the polysaccharopeptide (PSP), isolated from Chinese medicinal mushroom Coriolus versicolor, was able to enhance the cytotoxicity of certain S-phase targeted-drugs o …
In search of natural bioactive microbial compounds with adjuvant properties, we have previously showed that the polysaccharopeptide ( …
Polysaccharopeptide from Trametes versicolor blocks inflammatory osteoarthritis pain-morphine tolerance effects via activating cannabinoid type 2 receptor.
Wang K, Wang Z, Cui R, Chu H. Wang K, et al. Int J Biol Macromol. 2019 Apr 1;126:805-810. doi: 10.1016/j.ijbiomac.2018.12.212. Epub 2018 Dec 22. Int J Biol Macromol. 2019. PMID: 30584942
However, long-term use of morphine can cause morphine tolerance (MT), which limits the clinical application of opioids. Polysaccharopeptide from Trametes versicolor (TPSP) is a biologically active macromolecule that exerts anti-tumor, immune-enhancing and pain-relieving ef …
However, long-term use of morphine can cause morphine tolerance (MT), which limits the clinical application of opioids. Polysaccharopepti …
Polysaccharopeptide mimics ciclosporin-mediated Th1/Th2 cytokine balance for suppression of activated human T cell proliferation by MAPKp38 and STAT5 pathways.
Lee CL, Sit WH, Jiang PP, So IW, Wan JM. Lee CL, et al. J Pharm Pharmacol. 2008 Nov;60(11):1491-9. doi: 10.1211/jpp/60.11.0010. J Pharm Pharmacol. 2008. PMID: 18957170
The identification of agents that modulate the Th1/Th2 cytokines is therefore essential for controlling these diseases. We recently reported that polysaccharopeptide (PSP) from Coriolus versicolor exhibited ciclosporin-like activities to control aberrant T lymphocyte activ …
The identification of agents that modulate the Th1/Th2 cytokines is therefore essential for controlling these diseases. We recently reported …
219 results