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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 1
2007 1
2009 2
2010 2
2011 1
2012 1
2013 2
2014 1
2017 1
2020 1
2021 2
2024 0

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14 results

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Page 1
Spermatogenic failure and the Y chromosome.
Krausz C, Casamonti E. Krausz C, et al. Hum Genet. 2017 May;136(5):637-655. doi: 10.1007/s00439-017-1793-8. Epub 2017 Apr 29. Hum Genet. 2017. PMID: 28456834 Review.
Its highly repetitive structure predisposes this chromosome to deletion/duplication events and is responsible for Y-linked copy-number variations (CNVs) with clinical relevance. The AZF deletions remove genes with predicted spermatogenic function en block and are the most …
Its highly repetitive structure predisposes this chromosome to deletion/duplication events and is responsible for Y-linked copy-number varia …
Genetic causes of spermatogenic failure.
Massart A, Lissens W, Tournaye H, Stouffs K. Massart A, et al. Asian J Androl. 2012 Jan;14(1):40-8. doi: 10.1038/aja.2011.67. Epub 2011 Dec 5. Asian J Androl. 2012. PMID: 22138898 Free PMC article. Review.
Approximately 10%-15% of couples are infertile, and a male factor is involved in almost half of these cases. ...
Approximately 10%-15% of couples are infertile, and a male factor is involved in almost half of these cases. ...
Translational aspects of novel findings in genetics of male infertility-status quo 2021.
Laan M, Kasak L, Punab M. Laan M, et al. Br Med Bull. 2021 Dec 16;140(1):5-22. doi: 10.1093/bmb/ldab025. Br Med Bull. 2021. PMID: 34755838 Free PMC article. Review.
AREAS OF CONTROVERSY: Progress in mapping monogenic causes of quantitative spermatogenic failure, the major form of male infertility, has been slower. ...GROWING POINTS: Given the high genetic heterogeneity, an optimal approach to screen for heterogenous genetic cau …
AREAS OF CONTROVERSY: Progress in mapping monogenic causes of quantitative spermatogenic failure, the major form of male infer …
Monogenic causes of non-obstructive azoospermia: challenges, established knowledge, limitations and perspectives.
Kasak L, Laan M. Kasak L, et al. Hum Genet. 2021 Jan;140(1):135-154. doi: 10.1007/s00439-020-02112-y. Epub 2020 Jan 18. Hum Genet. 2021. PMID: 31955275 Review.
Non-obstructive azoospermia (NOA) is mostly explained by congenital factors leading to spermatogenic failure, such as chromosome abnormalities. The knowledge of the monogenic causes of NOA is very limited. ...Uncovering the loci and biological processes implicated i …
Non-obstructive azoospermia (NOA) is mostly explained by congenital factors leading to spermatogenic failure, such as chromoso …
Y chromosome and male infertility.
Krausz C, McElreavey K. Krausz C, et al. Front Biosci. 1999 Jan 15;4:E1-8. doi: 10.2741/krausz. Front Biosci. 1999. PMID: 9889182 Review.
Microdeletions of the long arm of the human Y chromosome are associated with spermatogenic failure and have been used to define three regions of Yq (AZFa, AZFb and AZFc) that are recurrently deleted in infertile males. ...Many of these genes encode proteins involved …
Microdeletions of the long arm of the human Y chromosome are associated with spermatogenic failure and have been used to defin …
Medical management of non-obstructive azoospermia.
Kumar R. Kumar R. Clinics (Sao Paulo). 2013;68 Suppl 1(Suppl 1):75-9. doi: 10.6061/clinics/2013(sup01)08. Clinics (Sao Paulo). 2013. PMID: 23503956 Free PMC article. Review.
Non-obstructive azoospermia is diagnosed in approximately 10% of infertile men. It represents a failure of spermatogenesis within the testis and, from a management standpoint, is due to either a lack of appropriate stimulation by gonadotropins or an intrinsic testic …
Non-obstructive azoospermia is diagnosed in approximately 10% of infertile men. It represents a failure of spermatogenesis wit …
Clinical Review#: State of the art for genetic testing of infertile men.
McLachlan RI, O'Bryan MK. McLachlan RI, et al. J Clin Endocrinol Metab. 2010 Mar;95(3):1013-24. doi: 10.1210/jc.2009-1925. Epub 2010 Jan 20. J Clin Endocrinol Metab. 2010. PMID: 20089613 Review.
Intracytoplasmic sperm injection (ICSI) now provides fertility in many cases of severe idiopathic spermatogenic failure and obstructive azoospermia. Genetic causes must be sought by systematic evaluation of infertile men and affected couples informed about the impli …
Intracytoplasmic sperm injection (ICSI) now provides fertility in many cases of severe idiopathic spermatogenic failure and ob …
Genetic susceptibility to male infertility: news from genome-wide association studies.
Aston KI. Aston KI. Andrology. 2014 May;2(3):315-21. doi: 10.1111/j.2047-2927.2014.00188.x. Epub 2014 Feb 19. Andrology. 2014. PMID: 24574159 Free article. Review.
Well-established genetic causes of male infertility are limited to Y chromosome microdeletions and Klinefelter's syndrome, together accounting for 10-20% of cases of severe spermatogenic failure. In addition to these, several genetic polymorphisms have been d …
Well-established genetic causes of male infertility are limited to Y chromosome microdeletions and Klinefelter's syndrome, together accounti …
Unravelling the genetics of spermatogenic failure.
Visser L, Repping S. Visser L, et al. Reproduction. 2010 Feb;139(2):303-7. doi: 10.1530/REP-09-0229. Epub 2009 Sep 23. Reproduction. 2010. PMID: 19776097 Review.
Subfertility, defined as the inability to conceive within 1 year of unprotected intercourse, affects 10-15% of couples. In up to 55% of couples, the male partner is diagnosed with spermatogenic failure, i.e. one or more semen parameters fall below the WHO cri …
Subfertility, defined as the inability to conceive within 1 year of unprotected intercourse, affects 10-15% of couples. In up to 55% …
Genetics of human male infertility.
Poongothai J, Gopenath TS, Manonayaki S. Poongothai J, et al. Singapore Med J. 2009 Apr;50(4):336-47. Singapore Med J. 2009. PMID: 19421675 Free article. Review.
Infertility is defined as a failure to conceive in a couple trying to reproduce for a period of two years without conception. ...Recently, a partial, novel Y chromosome 1.6-Mb deletion, designated "gr/gr" deletion, has been described specifically in infertile men with vary …
Infertility is defined as a failure to conceive in a couple trying to reproduce for a period of two years without conception. ...Rece …
14 results