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Blood coagulation factor XIII and factor XIII deficiency.
Dorgalaleh A, Rashidpanah J. Dorgalaleh A, et al. Blood Rev. 2016 Nov;30(6):461-475. doi: 10.1016/j.blre.2016.06.002. Epub 2016 Jun 16. Blood Rev. 2016. PMID: 27344554 Review.
Factor XIII (FXIII) is a multifunctional pro-gamma-transglutaminase that, in addition to its well-known role in hemostasis, has a crucial role in angiogenesis, maintenance of pregnancy, wound healing, bone metabolism, and even cardio protection. FXIII deficiency …
Factor XIII (FXIII) is a multifunctional pro-gamma-transglutaminase that, in addition to its well-known role in hemostasis, ha …
Factor XIII deficiency.
Hsieh L, Nugent D. Hsieh L, et al. Haemophilia. 2008 Nov;14(6):1190-200. doi: 10.1111/j.1365-2516.2008.01857.x. Haemophilia. 2008. PMID: 19141159 Review.
Inherited factor XIII (FXIII) deficiency is a rare bleeding disorder that can present with umbilical bleeding during the neonatal period, delayed soft tissue bruising, mucosal bleeding and life-threatening intracranial haemorrhage. FXIII deficiency has …
Inherited factor XIII (FXIII) deficiency is a rare bleeding disorder that can present with umbilical bleeding during th …
Factor XIII: Structure and Function.
Schroeder V, Kohler HP. Schroeder V, et al. Semin Thromb Hemost. 2016 Jun;42(4):422-8. doi: 10.1055/s-0036-1571341. Epub 2016 Mar 28. Semin Thromb Hemost. 2016. PMID: 27019464 Review.
Over the last two decades, it became evident that factor XIII (FXIII) is not only a crucial determinant of clot characteristics but also has potentially important functions in many various fields such as bone biology, immunity, and adipogenesis. ...In the B subun …
Over the last two decades, it became evident that factor XIII (FXIII) is not only a crucial determinant of clot characteristic …
Factor XIII Deficiency.
Karimi M, Bereczky Z, Cohan N, Muszbek L. Karimi M, et al. Semin Thromb Hemost. 2009 Jun;35(4):426-38. doi: 10.1055/s-0029-1225765. Epub 2009 Jul 13. Semin Thromb Hemost. 2009. PMID: 19598071 Review.
Factor XIII (FXIII) is a tetrameric zymogen (FXIII-A (2)B (2)) that is converted into an active transglutaminase (FXIIIa) by thrombin and Ca (2+) in the terminal phase of the clotting cascade. ...In addition, impaired wound healing and spontaneous abortion in women …
Factor XIII (FXIII) is a tetrameric zymogen (FXIII-A (2)B (2)) that is converted into an active transglutaminase (FXIIIa) by t …
Molecular and genetic mechanisms of factor XIII A subunit deficiency.
Ichinose A, Souri M, Izumi T, Takahashi N. Ichinose A, et al. Semin Thromb Hemost. 2000;26(1):5-10. doi: 10.1055/s-2000-9795. Semin Thromb Hemost. 2000. PMID: 10805274 Review.
Factor XIII is a proenzyme for a plasma transglutaminase. Factor XIII in plasma is a tetramer (A2B2) held together by noncovalent bonds, and the A subunit contains the active site. Recently, the three-dimensional structure of the A subunit …
Factor XIII is a proenzyme for a plasma transglutaminase. Factor XIII in plasma is a tetramer (A2B2) held togeth …
Hemorrhagic acquired factor XIII (13) deficiency and acquired hemorrhaphilia 13 revisited.
Ichinose A. Ichinose A. Semin Thromb Hemost. 2011 Jun;37(4):382-8. doi: 10.1055/s-0031-1276587. Epub 2011 Jul 30. Semin Thromb Hemost. 2011. PMID: 21805444 Review.
Coagulation factor XIII (F13) circulates in blood as a heterotetramer composed of an A subunit dimer and a B subunit dimer. ...Recently, consultations with physicians who have patients with hemorrhagic-acquired F13 deficiency with anti-F13 inhib …
Coagulation factor XIII (F13) circulates in blood as a heterotetramer composed of an A subunit dimer and a B subunit …
Factor XIII: congenital deficiency factor XIII, acquired deficiency, factor XIII A-subunit, and factor XIII B-subunit.
Tahlan A, Ahluwalia J. Tahlan A, et al. Arch Pathol Lab Med. 2014 Feb;138(2):278-81. doi: 10.5858/arpa.2012-0639-RS. Arch Pathol Lab Med. 2014. PMID: 24476525 Free article. Review.
Factor XIII (FXIII) is a transglutaminase consisting of 2 catalytic A subunits and 2 noncatalytic B subunits in plasma. ...Patients with acquired FXIII deficiency with inhibitors need immunosuppressive therapy in addition to factor replacements....
Factor XIII (FXIII) is a transglutaminase consisting of 2 catalytic A subunits and 2 noncatalytic B subunits in plasma. ...Pat …
Congenital blood coagulation factor XIII deficiency and successful deliveries: a review of the literature.
Asahina T, Kobayashi T, Takeuchi K, Kanayama N. Asahina T, et al. Obstet Gynecol Surv. 2007 Apr;62(4):255-60. doi: 10.1097/01.ogx.0000259176.03156.2b. Obstet Gynecol Surv. 2007. PMID: 17371605 Review.
Congenital deficiency of blood coagulation factor XIII is an uncommon, inherited disorder characterized by hemorrhagic diathesis, habitual abortions and defective wound healing. We analyzed 8 reported successful pregnancies in women with a congenital defic …
Congenital deficiency of blood coagulation factor XIII is an uncommon, inherited disorder characterized by hemorrhagic …
Advances in the treatment of bleeding disorders.
Peyvandi F, Garagiola I, Biguzzi E. Peyvandi F, et al. J Thromb Haemost. 2016 Nov;14(11):2095-2106. doi: 10.1111/jth.13491. Epub 2016 Oct 19. J Thromb Haemost. 2016. PMID: 27590165 Free article. Review.
Regarding von Willebrand disease, a recombinant von Willebrand factor was recently developed to control bleeding episodes in patients with this disease, in addition to available von Willebrand factor/factor VIII concentrates. ...Some improvements have recentl …
Regarding von Willebrand disease, a recombinant von Willebrand factor was recently developed to control bleeding episodes in patients …
Diagnosis and Management of Congenital and Acquired FXIII Deficiencies.
Muszbek L, Katona É. Muszbek L, et al. Semin Thromb Hemost. 2016 Jun;42(4):429-39. doi: 10.1055/s-0036-1572326. Epub 2016 Apr 12. Semin Thromb Hemost. 2016. PMID: 27071048 Review.
Inherited deficiency of FXIII A subunit (FXIII-A) is a rare (1:2,000,000) but very severe bleeding diathesis. ...Because of the high risk of intracranial bleeding, life-long prophylaxis, preferably using FXIII concentrate, is mandatory. In FXIII-B subunit …
Inherited deficiency of FXIII A subunit (FXIII-A) is a rare (1:2,000,000) but very severe bleeding diathesis. ...Because of th …
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