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Page 1
Common VKORC1 and GGCX polymorphisms associated with warfarin dose.
Wadelius M, Chen LY, Downes K, Ghori J, Hunt S, Eriksson N, Wallerman O, Melhus H, Wadelius C, Bentley D, Deloukas P. Wadelius M, et al. Pharmacogenomics J. 2005;5(4):262-70. doi: 10.1038/sj.tpj.6500313. Pharmacogenomics J. 2005. PMID: 15883587
Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients.
Michaud V, Vanier MC, Brouillette D, Roy D, Verret L, Noel N, Taillon I, O'Hara G, Gossard D, Champagne M, Goodman K, Renaud Y, Brown A, Phillips M, Ajami AM, Turgeon J. Michaud V, et al. Clin Pharmacol Ther. 2008 May;83(5):740-8. doi: 10.1038/sj.clpt.6100434. Epub 2007 Nov 14. Clin Pharmacol Ther. 2008. PMID: 18030307
Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.
Jorgensen AL, Al-Zubiedi S, Zhang JE, Keniry A, Hanson A, Hughes DA, Eker Dv, Stevens L, Hawkins K, Toh CH, Kamali F, Daly AK, Fitzmaurice D, Coffey A, Williamson PR, Park BK, Deloukas P, Pirmohamed M. Jorgensen AL, et al. Pharmacogenet Genomics. 2009 Oct;19(10):800-12. doi: 10.1097/FPC.0b013e3283317ab5. Pharmacogenet Genomics. 2009. PMID: 19752777 Free PMC article. Clinical Trial.
Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups.
Limdi NA, Wadelius M, Cavallari L, Eriksson N, Crawford DC, Lee MT, Chen CH, Motsinger-Reif A, Sagreiya H, Liu N, Wu AH, Gage BF, Jorgensen A, Pirmohamed M, Shin JG, Suarez-Kurtz G, Kimmel SE, Johnson JA, Klein TE, Wagner MJ; International Warfarin Pharmacogenetics Consortium. Limdi NA, et al. Blood. 2010 May 6;115(18):3827-34. doi: 10.1182/blood-2009-12-255992. Epub 2010 Mar 4. Blood. 2010. PMID: 20203262 Free PMC article.
12 results