PubMed (RefSeq) for id: 4503949

Year	Number of Results
1986	1
1987	1
1989	1
1991	1
1992	2
1993	4
1994	3
1995	3
1996	4
1997	3
1998	4
1999	6
2000	4
2001	4
2002	7
2003	5
2004	5
2005	8
2006	7
2007	11
2008	19
2009	23
2010	14
2011	14
2012	13
2013	8
2014	11
2015	7
2016	11
2017	12
2018	10
2019	8
2020	10
2021	12
2022	3
2024	0

1

Nitrosative stress induced by homocysteine thiolactone drives vascular cognitive impairments via GTP cyclohydrolase 1 S-nitrosylation in vivo.

Yin YL, Chen Y, Ren F, Wang L, Zhu ML, Lu JX, Wang QQ, Lu CB, Liu C, Bai YP, Wang SX, Wang JZ, Li P. Yin YL, et al. Redox Biol. 2022 Dec;58:102540. doi: 10.1016/j.redox.2022.102540. Epub 2022 Nov 13. Redox Biol. 2022. PMID: 36399957 Free PMC article.

2

CircLRFN5 inhibits the progression of glioblastoma via PRRX2/GCH1 mediated ferroptosis.

Jiang Y, Zhao J, Li R, Liu Y, Zhou L, Wang C, Lv C, Gao L, Cui D. Jiang Y, et al. J Exp Clin Cancer Res. 2022 Oct 20;41(1):307. doi: 10.1186/s13046-022-02518-8. J Exp Clin Cancer Res. 2022. PMID: 36266731 Free PMC article.

3

Association analysis of SYT11, FGF20, GCH1 rare variants in Parkinson's disease.

Pu JL, Lin ZH, Zheng R, Yan YQ, Xue NJ, Yin XZ, Zhang BR. Pu JL, et al. CNS Neurosci Ther. 2022 Jan;28(1):175-177. doi: 10.1111/cns.13745. Epub 2021 Oct 21. CNS Neurosci Ther. 2022. PMID: 34674384 Free PMC article. No abstract available.

4

GTP Cyclohydrolase I as a Potential Drug Target: New Insights into Its Allosteric Modulation via Normal Mode Analysis.

Khairallah A, Ross CJ, Tastan Bishop Ö. Khairallah A, et al. J Chem Inf Model. 2021 Sep 27;61(9):4701-4719. doi: 10.1021/acs.jcim.1c00898. Epub 2021 Aug 27. J Chem Inf Model. 2021. PMID: 34450011

5

Polymorphisms of Nav1.6 sodium channel, Brain-derived Neurotrophic Factor, Catechol-O-methyltransferase and Guanosine Triphosphate Cyclohydrolase 1 genes in trigeminal neuralgia.

Romero J, Costa GMF, Rocha LPC, Siqueira S, Moreira PR, Almeida-Leite CM. Romero J, et al. Clin Neurol Neurosurg. 2021 Sep;208:106880. doi: 10.1016/j.clineuro.2021.106880. Epub 2021 Aug 8. Clin Neurol Neurosurg. 2021. PMID: 34418703

6

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.

Huttlin EL, Bruckner RJ, Navarrete-Perea J, Cannon JR, Baltier K, Gebreab F, Gygi MP, Thornock A, Zarraga G, Tam S, Szpyt J, Gassaway BM, Panov A, Parzen H, Fu S, Golbazi A, Maenpaa E, Stricker K, Guha Thakurta S, Zhang T, Rad R, Pan J, Nusinow DP, Paulo JA, Schweppe DK, Vaites LP, Harper JW, Gygi SP. Huttlin EL, et al. Cell. 2021 May 27;184(11):3022-3040.e28. doi: 10.1016/j.cell.2021.04.011. Epub 2021 May 6. Cell. 2021. PMID: 33961781 Free PMC article.

7

Molecular and metabolic bases of tetrahydrobiopterin (BH₄) deficiencies.

Himmelreich N, Blau N, Thöny B. Himmelreich N, et al. Mol Genet Metab. 2021 Jun;133(2):123-136. doi: 10.1016/j.ymgme.2021.04.003. Epub 2021 Apr 19. Mol Genet Metab. 2021. PMID: 33903016 Review.

8

Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis.

Zhong GC, Zhao ZB, Cheng Y, Wang YB, Qiu C, Mao LH, Hu JJ, Cai D, Liu Y, Gong JP, Li SW. Zhong GC, et al. Free Radic Biol Med. 2021 May 20;168:81-94. doi: 10.1016/j.freeradbiomed.2021.03.025. Epub 2021 Mar 26. Free Radic Biol Med. 2021. PMID: 33781891

9

GCH1 mutations in hereditary spastic paraplegia.

Varghaei P, Yoon G, Estiar MA, Veyron S, Leveille E, Dupré N, Trempe JF, Rouleau GA, Gan-Or Z. Varghaei P, et al. Clin Genet. 2021 Jul;100(1):51-58. doi: 10.1111/cge.13955. Epub 2021 Mar 18. Clin Genet. 2021. PMID: 33713342

10

Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP.

Ebenhoch R, Bauer M, Reinert D, Kersting A, Huber S, Schmid A, Hinz I, Feiler M, Müller K, Nar H. Ebenhoch R, et al. J Struct Biol. 2021 Mar;213(1):107691. doi: 10.1016/j.jsb.2020.107691. Epub 2020 Dec 31. J Struct Biol. 2021. PMID: 33387654 Free article.

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