PubMed (MeSH Keyword) for id: 21679027

Year	Number of Results
2011	3
2012	6
2013	3
2014	2
2015	1
2016	4
2017	4
2018	2
2019	1
2020	3
2021	7
2022	4
2023	1
2024	0

1

The Natural Products Withaferin A and Withanone from the Medicinal Herb Withania somnifera Are Covalent Inhibitors of the SARS-CoV-2 Main Protease.

Chakraborty S, Mallick D, Goswami M, Guengerich FP, Chakrabarty A, Chowdhury G. Chakraborty S, et al. J Nat Prod. 2022 Oct 28;85(10):2340-2350. doi: 10.1021/acs.jnatprod.2c00521. Epub 2022 Sep 13. J Nat Prod. 2022. PMID: 36098617

2

Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A and Withanone.

Malik V, Radhakrishnan N, Kaul SC, Wadhwa R, Sundar D. Malik V, et al. Biomolecules. 2022 Jan 26;12(2):212. doi: 10.3390/biom12020212. Biomolecules. 2022. PMID: 35204712 Free PMC article.

3

Natural phytocompounds physalin D, withaferin a and withanone target L-asparaginase of Mycobacterium tuberculosis: a molecular dynamics study.

Sharma D, Saini R, Mishra A. Sharma D, et al. J Biomol Struct Dyn. 2023 Apr;41(7):2645-2659. doi: 10.1080/07391102.2022.2036239. Epub 2022 Feb 8. J Biomol Struct Dyn. 2023. PMID: 35132949

4

Effect of Ashwagandha Withanolides on Muscle Cell Differentiation.

Wang J, Zhang H, Kaul A, Li K, Priyandoko D, Kaul SC, Wadhwa R. Wang J, et al. Biomolecules. 2021 Oct 4;11(10):1454. doi: 10.3390/biom11101454. Biomolecules. 2021. PMID: 34680087 Free PMC article.

5

Withanone Ameliorates Stress Symptoms in Caenorhabditis Elegans by Acting through Serotonin Receptors.

Naß J, Efferth T. Naß J, et al. Pharmacopsychiatry. 2021 Sep;54(5):215-223. doi: 10.1055/a-1349-3870. Epub 2021 May 6. Pharmacopsychiatry. 2021. PMID: 33957677

6

Withanone from Withania somnifera Attenuates SARS-CoV-2 RBD and Host ACE2 Interactions to Rescue Spike Protein Induced Pathologies in Humanized Zebrafish Model.

Balkrishna A, Pokhrel S, Singh H, Joshi M, Mulay VP, Haldar S, Varshney A. Balkrishna A, et al. Drug Des Devel Ther. 2021 Mar 11;15:1111-1133. doi: 10.2147/DDDT.S292805. eCollection 2021. Drug Des Devel Ther. 2021. PMID: 33737804 Free PMC article.

7

Computational Insights into the Potential of Withaferin-A, Withanone and Caffeic Acid Phenethyl Ester for Treatment of Aberrant-EGFR Driven Lung Cancers.

Malik V, Kumar V, Kaul SC, Wadhwa R, Sundar D. Malik V, et al. Biomolecules. 2021 Jan 26;11(2):160. doi: 10.3390/biom11020160. Biomolecules. 2021. PMID: 33530424 Free PMC article.

8

Molecular dynamics simulations and experimental studies reveal differential permeability of withaferin-A and withanone across the model cell membrane.

Wadhwa R, Yadav NS, Katiyar SP, Yaguchi T, Lee C, Ahn H, Yun CO, Kaul SC, Sundar D. Wadhwa R, et al. Sci Rep. 2021 Jan 27;11(1):2352. doi: 10.1038/s41598-021-81729-z. Sci Rep. 2021. PMID: 33504873 Free PMC article.

9

Elucidation of plasma protein binding, blood partitioning, permeability, CYP phenotyping and CYP inhibition studies of Withanone using validated UPLC method: An active constituent of neuroprotective herb Ashwagandha.

Singh SK, Valicherla GR, Bikkasani AK, Cheruvu SH, Hossain Z, Taneja I, Ahmad H, Raju KSR, Sangwan NS, Singh SK, Dwivedi AK, Wahajuddin M, Gayen JR. Singh SK, et al. J Ethnopharmacol. 2021 Apr 24;270:113819. doi: 10.1016/j.jep.2021.113819. Epub 2021 Jan 16. J Ethnopharmacol. 2021. PMID: 33460762

10

Withanone and Withaferin-A are predicted to interact with transmembrane protease serine 2 (TMPRSS2) and block entry of SARS-CoV-2 into cells.

Kumar V, Dhanjal JK, Bhargava P, Kaul A, Wang J, Zhang H, Kaul SC, Wadhwa R, Sundar D. Kumar V, et al. J Biomol Struct Dyn. 2022 Jan;40(1):1-13. doi: 10.1080/07391102.2020.1775704. Epub 2020 Jun 16. J Biomol Struct Dyn. 2022. PMID: 32469279 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

31 results

Results by year