PubMed (GeneRIF) for id: 59350

Year	Number of Results
2002	1
2004	4
2005	8
2006	4
2007	3
2008	6
2009	13
2010	3
2011	2
2012	5
2013	6
2014	2
2015	4
2016	4
2019	2
2020	1
2021	2
2022	1
2024	0

1

Characterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models.

Illiano S, Poirier B, Minoletti C, Pasquier O, Riva L, Chenede X, Menguy I, Guillotel M, Prigent P, Le Claire S, Gillot F, Thill G, Lo Presti F, Corbier A, Le Bail JC, Grailhe P, Monteagudo E, Ingenito R, Bianchi E, Philippo C, Duclos O, Mallart S, Bathgate R, Janiak P. Illiano S, et al. Sci Rep. 2022 Nov 28;12(1):20435. doi: 10.1038/s41598-022-24716-2. Sci Rep. 2022. PMID: 36443381 Free PMC article.

2

Identification of a distal RXFP1 gene enhancer with differential activity in fibrotic lung fibroblasts involving AP-1.

Chen TY, Li X, Goobie GC, Hung CH, Hung TK, Hamilton K, Bahudhanapati H, Tan J, Kass DJ, Zhang Y. Chen TY, et al. PLoS One. 2021 Dec 31;16(12):e0254466. doi: 10.1371/journal.pone.0254466. eCollection 2021. PLoS One. 2021. PMID: 34972106 Free PMC article.

3

Structural Insights into the Unique Modes of Relaxin-Binding and Tethered-Agonist Mediated Activation of RXFP1 and RXFP2.

Sethi A, Bruell S, Ryan T, Yan F, Tanipour MH, Mok YF, Draper-Joyce C, Khandokar Y, Metcalfe RD, Griffin MDW, Scott DJ, Hossain MA, Petrie EJ, Bathgate RAD, Gooley PR. Sethi A, et al. J Mol Biol. 2021 Oct 15;433(21):167217. doi: 10.1016/j.jmb.2021.167217. Epub 2021 Aug 26. J Mol Biol. 2021. PMID: 34454945

4

The anti-fibrotic actions of relaxin are mediated through AT₂ R-associated protein phosphatases via RXFP1-AT₂ R functional crosstalk in human cardiac myofibroblasts.

Wang C, Pinar AA, Widdop RE, Hossain MA, Bathgate RAD, Denton KM, Kemp-Harper BK, Samuel CS. Wang C, et al. FASEB J. 2020 Jun;34(6):8217-8233. doi: 10.1096/fj.201902506R. Epub 2020 Apr 16. FASEB J. 2020. PMID: 32297670

5

Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.

Kaftanovskaya EM, Ng HH, Soula M, Rivas B, Myhr C, Ho BA, Cervantes BA, Shupe TD, Devarasetty M, Hu X, Xu X, Patnaik S, Wilson KJ, Barnaeva E, Ferrer M, Southall NT, Marugan JJ, Bishop CE, Agoulnik IU, Agoulnik AI. Kaftanovskaya EM, et al. FASEB J. 2019 Nov;33(11):12435-12446. doi: 10.1096/fj.201901046R. Epub 2019 Aug 16. FASEB J. 2019. PMID: 31419161 Free PMC article.

6

MicroRNA-144-3p targets relaxin/insulin-like family peptide receptor 1 (RXFP1) expression in lung fibroblasts from patients with idiopathic pulmonary fibrosis.

Bahudhanapati H, Tan J, Dutta JA, Strock SB, Sembrat J, Àlvarez D, Rojas M, Jäger B, Prasse A, Zhang Y, Kass DJ. Bahudhanapati H, et al. J Biol Chem. 2019 Mar 29;294(13):5008-5022. doi: 10.1074/jbc.RA118.004910. Epub 2019 Feb 1. J Biol Chem. 2019. PMID: 30709904 Free PMC article.

7

Hormone receptor expression in human fascial tissue.

Fede C, Albertin G, Petrelli L, Sfriso MM, Biz C, De Caro R, Stecco C. Fede C, et al. Eur J Histochem. 2016 Nov 2;60(4):2710. doi: 10.4081/ejh.2016.2710. Eur J Histochem. 2016. PMID: 28076930 Free PMC article.

8

Expression of RXFP1 Is Decreased in Idiopathic Pulmonary Fibrosis. Implications for Relaxin-based Therapies.

Tan J, Tedrow JR, Dutta JA, Juan-Guardela B, Nouraie M, Chu Y, Trejo Bittar H, Ramani K, Biswas PS, Veraldi KL, Kaminski N, Zhang Y, Kass DJ. Tan J, et al. Am J Respir Crit Care Med. 2016 Dec 1;194(11):1392-1402. doi: 10.1164/rccm.201509-1865OC. Am J Respir Crit Care Med. 2016. PMID: 27310652 Free PMC article.

9

The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1.

Sethi A, Bruell S, Patil N, Hossain MA, Scott DJ, Petrie EJ, Bathgate RAD, Gooley PR. Sethi A, et al. Nat Commun. 2016 Apr 18;7:11344. doi: 10.1038/ncomms11344. Nat Commun. 2016. PMID: 27088579 Free PMC article.

10

Endometrial LGR7 expression and implantation failure.

Campitiello MR, Caprio F, Mele D, D'eufemia D, Colacurci N, De Franciscis P. Campitiello MR, et al. Gynecol Endocrinol. 2016 Jun;32(6):449-52. doi: 10.3109/09513590.2015.1127912. Epub 2016 Jan 13. Gynecol Endocrinol. 2016. PMID: 26761440

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