PubMed (GeneRIF) for id: 253260

Year	Number of Results
2005	1
2006	3
2007	3
2008	4
2009	6
2010	12
2011	6
2012	5
2013	11
2014	3
2015	11
2016	6
2017	11
2018	11
2019	6
2020	11
2021	4
2022	4
2023	4
2024	1

1

Rictor mediates p53 deactivation to facilitate the malignant transformation of hepatocytes and promote hepatocarcinogenesis.

Wang C, Kang H, Yi Y, Ding Y, Wang F, Luo J, Ye M, Hong Y, Xia C, Yan J, Liu L, Liu J, Zhong Z, Zhang Z, Zhao Q, Chang Y. Wang C, et al. J Transl Med. 2023 Dec 18;21(1):919. doi: 10.1186/s12967-023-04799-9. J Transl Med. 2023. PMID: 38110956 Free PMC article.

2

RBM45 reprograms lipid metabolism promoting hepatocellular carcinoma via Rictor and ACSL1/ACSL4.

Wang C, Chen Z, Yi Y, Ding Y, Xu F, Kang H, Lin K, Shu X, Zhong Z, Zhang Z, Liu J, Xu Z, Liu L, He X, Chang Y, Zhao Q. Wang C, et al. Oncogene. 2024 Jan;43(5):328-340. doi: 10.1038/s41388-023-02902-4. Epub 2023 Dec 1. Oncogene. 2024. PMID: 38040804

3

Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing.

Sztankovics D, Krencz I, Moldvai D, Dankó T, Nagy Á, Nagy N, Bedics G, Rókusz A, Papp G, Tőkés AM, Pápay J, Sápi Z, Dezső K, Bödör C, Sebestyén A. Sztankovics D, et al. Sci Rep. 2023 Nov 10;13(1):19610. doi: 10.1038/s41598-023-46927-x. Sci Rep. 2023. PMID: 37949943 Free PMC article.

4

UBXN2A suppresses the Rictor-mTORC2 signaling pathway, an established tumorigenic pathway in human colorectal cancer.

Sane S, Srinivasan R, Potts RA, Eikanger M, Zagirova D, Freeling J, Reihe CA, Antony RM, Gupta BK, Lynch D, Bleeker J, Turaihi H, Pillatzki A, Zhou W, Luo X, Linnebacher M, Agany D, Zohim EG, Humphrey LE, Black AR, Rezvani K. Sane S, et al. Oncogene. 2023 May;42(21):1763-1776. doi: 10.1038/s41388-023-02686-7. Epub 2023 Apr 10. Oncogene. 2023. PMID: 37037900 Free PMC article.

5

Epithelial-mesenchymal reprogramming by KLF4-regulated Rictor expression contributes to metastasis of non-small cell lung cancer cells.

Zhou H, Guan Q, Hou X, Liu L, Zhou L, Li W, Liu H. Zhou H, et al. Int J Biol Sci. 2022 Jul 18;18(13):4869-4883. doi: 10.7150/ijbs.73548. eCollection 2022. Int J Biol Sci. 2022. PMID: 35982899 Free PMC article.

6

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

Luciano AK, Korobkina ED, Lyons SP, Haley JA, Fluharty SM, Jung SM, Kettenbach AN, Guertin DA. Luciano AK, et al. J Biol Chem. 2022 Oct;298(10):102379. doi: 10.1016/j.jbc.2022.102379. Epub 2022 Aug 13. J Biol Chem. 2022. PMID: 35973513 Free PMC article.

7

Interactions between mTORC2 core subunits Rictor and mSin1 dictate selective and context-dependent phosphorylation of substrate kinases SGK1 and Akt.

Yu Z, Chen J, Takagi E, Wang F, Saha B, Liu X, Joubert LM, Gleason CE, Jin M, Li C, Nowotny C, Agard D, Cheng Y, Pearce D. Yu Z, et al. J Biol Chem. 2022 Sep;298(9):102288. doi: 10.1016/j.jbc.2022.102288. Epub 2022 Aug 1. J Biol Chem. 2022. PMID: 35926713 Free PMC article.

8

LncRNA KCNQ1OT1 promotes osteogenic differentiation via miR-205-5p/RICTOR axis.

Yang JJ, Peng WX, Zhang MB. Yang JJ, et al. Exp Cell Res. 2022 Jun 1;415(1):113119. doi: 10.1016/j.yexcr.2022.113119. Epub 2022 Mar 24. Exp Cell Res. 2022. PMID: 35341776

9

An RNA-RNA crosstalk network involving HMGB1 and RICTOR facilitates hepatocellular carcinoma tumorigenesis by promoting glutamine metabolism and impedes immunotherapy by PD-L1+ exosomes activity.

Wei Y, Tang X, Ren Y, Yang Y, Song F, Fu J, Liu S, Yu M, Chen J, Wang S, Zhang K, Tan Y, Han Z, Wei L, Zhang B, Cheng Z, Li L, Wang H. Wei Y, et al. Signal Transduct Target Ther. 2021 Dec 17;6(1):421. doi: 10.1038/s41392-021-00801-2. Signal Transduct Target Ther. 2021. PMID: 34916485 Free PMC article.

10

Rictor, an essential component of mTOR complex 2, undergoes caspase-mediated cleavage during apoptosis induced by multiple stimuli.

Zhao L, Zhu L, Oh YT, Qian G, Chen Z, Sun SY. Zhao L, et al. Apoptosis. 2021 Jun;26(5-6):338-347. doi: 10.1007/s10495-021-01676-y. Epub 2021 Apr 27. Apoptosis. 2021. PMID: 33905036

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