PubMed for id: 134

Year	Number of Results
1987	1
1989	1
1991	1
1992	3
1993	2
1994	2
1995	1
1996	1
1997	2
1999	4
2000	1
2001	4
2002	4
2003	7
2004	6
2005	2
2006	5
2007	4
2008	10
2009	16
2010	9
2011	8
2012	9
2013	5
2014	5
2015	8
2016	8
2017	8
2018	4
2019	3
2020	6
2021	6
2022	2
2023	1
2024	1

1

The ADORA1 mutation linked to early-onset Parkinson's disease alters adenosine A₁-A_2A receptor heteromer formation and function.

Sarasola LI, Del Torrent CL, Pérez-Arévalo A, Argerich J, Casajuana-Martín N, Chevigné A, Fernández-Dueñas V, Ferré S, Pardo L, Ciruela F. Sarasola LI, et al. Biomed Pharmacother. 2022 Dec;156:113896. doi: 10.1016/j.biopha.2022.113896. Epub 2022 Oct 21. Biomed Pharmacother. 2022. PMID: 36279718 Free article.

2

Crystal structure of the α_1B-adrenergic receptor reveals molecular determinants of selective ligand recognition.

Deluigi M, Morstein L, Schuster M, Klenk C, Merklinger L, Cridge RR, de Zhang LA, Klipp A, Vacca S, Vaid TM, Mittl PRE, Egloff P, Eberle SA, Zerbe O, Chalmers DK, Scott DJ, Plückthun A. Deluigi M, et al. Nat Commun. 2022 Jan 19;13(1):382. doi: 10.1038/s41467-021-27911-3. Nat Commun. 2022. PMID: 35046410 Free PMC article.

3

Functional Impact of the G279S Substitution in the Adenosine A₁-Receptor (A₁R-G279S^7.44), a Mutation Associated with Parkinson's Disease.

Nasrollahi-Shirazi S, Szöllösi D, Yang Q, Muratspahic E, El-Kasaby A, Sucic S, Stockner T, Nanoff C, Freissmuth M. Nasrollahi-Shirazi S, et al. Mol Pharmacol. 2020 Sep;98(3):250-266. doi: 10.1124/molpharm.120.000003. Mol Pharmacol. 2020. PMID: 32817461 Free PMC article.

4

NanoBiT Complementation to Monitor Agonist-Induced Adenosine A₁ Receptor Internalization.

Soave M, Kellam B, Woolard J, Briddon SJ, Hill SJ. Soave M, et al. SLAS Discov. 2020 Feb;25(2):186-194. doi: 10.1177/2472555219880475. Epub 2019 Oct 4. SLAS Discov. 2020. PMID: 31583945 Free PMC article.

5

Cognitive impairments by alcohol and sleep deprivation indicate trait characteristics and a potential role for adenosine A₁ receptors.

Elmenhorst EM, Elmenhorst D, Benderoth S, Kroll T, Bauer A, Aeschbach D. Elmenhorst EM, et al. Proc Natl Acad Sci U S A. 2018 Jul 31;115(31):8009-8014. doi: 10.1073/pnas.1803770115. Epub 2018 Jul 16. Proc Natl Acad Sci U S A. 2018. PMID: 30012607 Free PMC article. Clinical Trial.

6

Recovery sleep after extended wakefulness restores elevated A₁ adenosine receptor availability in the human brain.

Elmenhorst D, Elmenhorst EM, Hennecke E, Kroll T, Matusch A, Aeschbach D, Bauer A. Elmenhorst D, et al. Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4243-4248. doi: 10.1073/pnas.1614677114. Epub 2017 Apr 3. Proc Natl Acad Sci U S A. 2017. PMID: 28373571 Free PMC article.

7

Structure of the Adenosine A₁ Receptor Reveals the Basis for Subtype Selectivity.

Glukhova A, Thal DM, Nguyen AT, Vecchio EA, Jörg M, Scammells PJ, May LT, Sexton PM, Christopoulos A. Glukhova A, et al. Cell. 2017 Feb 23;168(5):867-877.e13. doi: 10.1016/j.cell.2017.01.042. Cell. 2017. PMID: 28235198 Free article.

8

ADORA1 mutations are not a common cause of Parkinson's disease and dementia with Lewy bodies.

Blauwendraat C, Nalls MA, Federoff M, Pletnikova O, Ding J, Letson C, Geiger JT, Gibbs JR, Hernandez DG, Troncoso JC, Simón-Sánchez J, Scholz SW; International Parkinson's Disease Genomics Consortium. Blauwendraat C, et al. Mov Disord. 2017 Feb;32(2):298-299. doi: 10.1002/mds.26886. Epub 2016 Dec 17. Mov Disord. 2017. PMID: 27987235 Free PMC article. No abstract available.

9

Extracellular Loop 2 of the Adenosine A1 Receptor Has a Key Role in Orthosteric Ligand Affinity and Agonist Efficacy.

Nguyen AT, Baltos JA, Thomas T, Nguyen TD, Muñoz LL, Gregory KJ, White PJ, Sexton PM, Christopoulos A, May LT. Nguyen AT, et al. Mol Pharmacol. 2016 Dec;90(6):703-714. doi: 10.1124/mol.116.105007. Epub 2016 Sep 28. Mol Pharmacol. 2016. PMID: 27683014

10

Role of the Second Extracellular Loop of the Adenosine A1 Receptor on Allosteric Modulator Binding, Signaling, and Cooperativity.

Nguyen AT, Vecchio EA, Thomas T, Nguyen TD, Aurelio L, Scammells PJ, White PJ, Sexton PM, Gregory KJ, May LT, Christopoulos A. Nguyen AT, et al. Mol Pharmacol. 2016 Dec;90(6):715-725. doi: 10.1124/mol.116.105015. Epub 2016 Sep 28. Mol Pharmacol. 2016. PMID: 27683013

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