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Identification of alverine and benfluorex as HNF4α activators.
Lee SH, Athavankar S, Cohen T, Piran R, Kiselyuk A, Levine F. Lee SH, et al. Among authors: kiselyuk a. ACS Chem Biol. 2013 Aug 16;8(8):1730-6. doi: 10.1021/cb4000986. Epub 2013 May 29. ACS Chem Biol. 2013. PMID: 23675775 Free PMC article.
HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter.
Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, Higginbotham J, Cashman J, Freeze H, Itkin-Ansari P, Dawson MI, Schroeder F, Cang Y, Mercola M, Levine F. Kiselyuk A, et al. Chem Biol. 2012 Jul 27;19(7):806-18. doi: 10.1016/j.chembiol.2012.05.014. Chem Biol. 2012. PMID: 22840769 Free PMC article.
Derivation of a retinoid X receptor scaffold from peroxisome proliferator-activated receptor gamma ligand 1-Di(1H-indol-3-yl)methyl-4-trifluoromethylbenzene.
Dawson MI, Ye M, Cao X, Farhana L, Hu QY, Zhao Y, Xu LP, Kiselyuk A, Correa RG, Yang L, Hou T, Reed JC, Itkin-Ansari P, Levine F, Sanner MF, Fontana JA, Zhang XK. Dawson MI, et al. Among authors: kiselyuk a. ChemMedChem. 2009 Jul;4(7):1106-19. doi: 10.1002/cmdc.200800447. ChemMedChem. 2009. PMID: 19378296 Free PMC article.