Abstract
A 50-year-old diabetic man developed necrotizing scleritis with adjacent keratitis 4 weeks after uncomplicated cataract extraction and intraocular lens implantation through a scleral tunnel incision. Cultures of the necrotic sclera grew Rizopus species. Severe destruction of the globe ensued despite topical, subconjunctival, and intravenous amphotericin B, in combination with hyperbaric oxygen therapy. Histopathological examination of the enucleated globe was consistent with Rhizopus infection. One year later, the patient was well without signs of recurrence.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Antifungal Agents / therapeutic use
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Diabetes Mellitus, Type 1 / complications*
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Eye Enucleation
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Eye Infections, Fungal / etiology*
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Eye Infections, Fungal / pathology
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Eye Infections, Fungal / therapy
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Humans
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Keratitis / microbiology
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Keratitis / pathology
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Keratitis / therapy
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Lens Implantation, Intraocular / adverse effects
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Male
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Middle Aged
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Mucormycosis / etiology*
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Mucormycosis / pathology
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Mucormycosis / therapy
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Phacoemulsification / adverse effects
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Postoperative Complications / microbiology*
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Postoperative Complications / pathology
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Postoperative Complications / therapy
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Rhizopus / isolation & purification*
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Sclera / microbiology
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Sclera / pathology
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Scleritis / microbiology*
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Scleritis / pathology
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Scleritis / therapy