Discrepancies between results by E-test and standard microbroth dilution testing of Streptococcus pneumoniae for susceptibility to vancomycin

F B Hashemi; G E Schutze; E O Mason Jr

doi:10.1128/jcm.34.6.1546-1547.1996

Discrepancies between results by E-test and standard microbroth dilution testing of Streptococcus pneumoniae for susceptibility to vancomycin

J Clin Microbiol. 1996 Jun;34(6):1546-7. doi: 10.1128/jcm.34.6.1546-1547.1996.

Authors

F B Hashemi¹, G E Schutze, E O Mason Jr

Affiliation

¹ Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, USA.

Abstract

Vancomycin susceptibility testing of Streptococcus pneumoniae by the E-test consistently resulted in MICs that were at the upper limit of the 1-microgram/ml susceptible category defined by current National Committee for Clinical Laboratory Standards guidelines and were always higher than MICs obtained by microbroth dilution. Three of five E-test results for S. pneumoniae ATCC 49619 were higher than the acceptable limits.

Publication types

Comparative Study

MeSH terms

Anti-Bacterial Agents / pharmacology*
Child
Drug Resistance, Microbial
Evaluation Studies as Topic
Humans
Microbial Sensitivity Tests / methods*
Microbial Sensitivity Tests / standards
Pneumococcal Infections / drug therapy
Pneumococcal Infections / microbiology
Reference Standards
Streptococcus pneumoniae / drug effects*
Streptococcus pneumoniae / isolation & purification
Vancomycin / pharmacology*

Substances

Anti-Bacterial Agents
Vancomycin