Successful treatment of intraoperative malignant hyperthermia during renal transplantation

J A Goss; D C Brennan; B T Miller; S Shenoy; S McClure; T K Howard; M W Flye

Successful treatment of intraoperative malignant hyperthermia during renal transplantation

Clin Transplant. 1996 Apr;10(2):195-8.

Authors

J A Goss¹, D C Brennan, B T Miller, S Shenoy, S McClure, T K Howard, M W Flye

Affiliation

¹ Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

PMID: 8664518

Abstract

Malignant hyperthermia is a complication of general anesthesia that is especially problematic if it occurs during renal transplantation because myoglobinemia, shock, and ischemia play a role in injuring the transplanted kidney. In this report, we describe a case of malignant hyperthermia, its clinical course, and the measures taken to successfully treat it and preserve the function of a kidney allograft.

Publication types

Case Reports

MeSH terms

Adult
Anesthesia, General / adverse effects
Dantrolene / therapeutic use
Humans
Intraoperative Complications / therapy*
Ischemia / physiopathology
Kidney / physiopathology
Kidney Transplantation* / adverse effects
Kidney Transplantation* / physiology
Male
Malignant Hyperthermia / physiopathology
Malignant Hyperthermia / therapy*
Muscle Relaxants, Central / therapeutic use
Myoglobin / blood
Renal Dialysis
Shock / physiopathology
Transplantation, Homologous
Treatment Outcome

Substances

Muscle Relaxants, Central
Myoglobin
Dantrolene