Production of immunoreactive pancreatic growth hormone-releasing factor in small cell carcinoma of the lung

K Yamaguchi; K Abe; M Suzuki; I Adachi; S Kimura; A Shimada; H Ohno; A Kanai; T Kameya

Production of immunoreactive pancreatic growth hormone-releasing factor in small cell carcinoma of the lung

Gan. 1983 Dec;74(6):814-7.

Authors

K Yamaguchi, K Abe, M Suzuki, I Adachi, S Kimura, A Shimada, H Ohno, A Kanai, T Kameya

PMID: 6321286

Abstract

A specific and sensitive radioimmunoassay for human pancreatic growth hormone-releasing factor (hpGRF) was developed. Using this radioimmunoassay, it was found that immunoreactive hpGRF (which is present in hypothalamic tissues) of at least two different molecular sizes is often produced by small cell carcinoma of the lung.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Breast Neoplasms / metabolism
Carcinoma, Small Cell / metabolism*
Chromatography, Gel
Growth Hormone-Releasing Hormone / metabolism*
Humans
Hypothalamus / metabolism*
Lung / metabolism
Lung Neoplasms / metabolism*
Molecular Weight
Peptide Fragments / metabolism*
Radioimmunoassay
Stomach Neoplasms / metabolism

Substances

Peptide Fragments
somatotropin releasing factor 40
somatotropin releasing hormone (1-37)
somatotropin releasing hormone (1-44)amide
Growth Hormone-Releasing Hormone