Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy

Neurosci Bull. 2022 Jan;38(1):99-103. doi: 10.1007/s12264-021-00783-9. Epub 2021 Nov 5.
No abstract available

Publication types

  • Letter

MeSH terms

  • Apoptosis / physiology
  • Autophagy* / physiology
  • Humans
  • Huntingtin Protein
  • Huntington Disease*
  • Intracellular Signaling Peptides and Proteins
  • Protein Serine-Threonine Kinases

Substances

  • HTT protein, human
  • Huntingtin Protein
  • Intracellular Signaling Peptides and Proteins
  • HIPK3 protein, human
  • Protein Serine-Threonine Kinases