A resource of targeted mutant mouse lines for 5,061 genes

Nat Genet. 2021 Apr;53(4):416-419. doi: 10.1038/s41588-021-00825-y.

Abstract

The International Mouse Phenotyping Consortium reports the generation of new mouse mutant strains for over 5,000 genes, including 2,850 novel null, 2,987 novel conditional- ready, and 4,433 novel reporter alleles.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Gene Deletion*
  • Genetic Association Studies*
  • Genome*
  • Genotype*
  • Information Dissemination
  • International Cooperation
  • Internet
  • Mice
  • Mice, Knockout
  • Mouse Embryonic Stem Cells / cytology
  • Mouse Embryonic Stem Cells / metabolism
  • Mutagenesis
  • Phenotype