Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography

Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1534-1548. doi: 10.1161/ATVBAHA.120.315210. Epub 2021 Feb 4.

Abstract

[Figure: see text].

Keywords: aneurysm, dissection; angiotensin II; aortic aneurysm; contrast media; nanoparticles.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Angiotensin II
  • Animals
  • Aorta / diagnostic imaging*
  • Aorta / pathology
  • Aortic Aneurysm / chemically induced
  • Aortic Aneurysm / diagnostic imaging*
  • Aortic Aneurysm / pathology
  • Aortic Dissection / chemically induced
  • Aortic Dissection / diagnostic imaging*
  • Aortic Dissection / pathology
  • Aortic Rupture / chemically induced
  • Aortic Rupture / diagnostic imaging*
  • Aortic Rupture / pathology
  • Aortography*
  • Computed Tomography Angiography*
  • Contrast Media*
  • Diet, High-Fat
  • Dilatation, Pathologic
  • Disease Models, Animal
  • Disease Progression
  • Early Diagnosis
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Nanoparticles*
  • Predictive Value of Tests
  • Time Factors
  • Triiodobenzoic Acids*
  • X-Ray Microtomography*

Substances

  • Contrast Media
  • Triiodobenzoic Acids
  • Angiotensin II
  • iodixanol