Hepatic abscesses due to Clostridium septicum infection and its association with colonic adenocarcinoma: a case report and literature review

Clin J Gastroenterol. 2020 Feb;13(1):66-72. doi: 10.1007/s12328-019-01002-9. Epub 2019 Jun 12.

Abstract

Clostridium septicum is an uncommon cause of pyogenic liver abscess but has been reported in the literature, most commonly in the setting of underlying colorectal or hematologic malignancies. Herein, we present a case of a patient with C. septicum bacteremia resulting in innumerable necrotic liver abscesses in the presence of metastatic colonic adenocarcinoma and also review the literature about previous reports of C. septicum as the etiology of hepatic abscess.

Keywords: Clostridium septicum bacteremia; Liver/hepatic abscess; Metastatic colon cancer.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / complications*
  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / pathology
  • Bacteremia / complications*
  • Bacteremia / diagnosis
  • Bacteremia / therapy
  • Clostridium Infections / complications*
  • Clostridium Infections / diagnosis
  • Clostridium Infections / therapy
  • Clostridium septicum*
  • Colonic Neoplasms / complications*
  • Colonic Neoplasms / diagnosis
  • Colonic Neoplasms / pathology
  • Humans
  • Liver Abscess, Pyogenic / complications*
  • Liver Abscess, Pyogenic / diagnostic imaging
  • Liver Abscess, Pyogenic / therapy
  • Liver Neoplasms / complications*
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / secondary
  • Male
  • Middle Aged