Newly Diagnosed Optic Pathway Glioma During Pregnancy

World Neurosurg. 2019 Jul:127:58-62. doi: 10.1016/j.wneu.2019.02.207. Epub 2019 Mar 13.

Abstract

Background: Optic pathway gliomas (OPGs) are relatively rare, and their presentation after the first decade of life is even less common. Although many treatment options exist, surgery is typically reserved for tumors significantly compressing surrounding structures. Pregnancy can complicate the management of these tumors, as fetal developmental considerations limit the ways in which they are imaged and treated.

Case description: In this report we detail the case of a 27-year-old pregnant woman who was found to have an OPG during her third trimester. After a decline in this patient's vision and clinical status, a decision was made to induce labor at 31 weeks so that her disease could be more thoroughly addressed.

Conclusions: While OPGs are typically benign tumors, pregnancy complicates their management significantly. Contrast media and anesthesia pose significant risks to the fetus, while pregnancy may contribute to increased rates of tumor growth and clinical deterioration. Managing OPGs in pregnant patients thus requires balancing the risks to the fetus and patient.

Keywords: Optic pathway glioma; Pilocytic astrocytoma; Pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Optic Nerve Glioma / complications
  • Optic Nerve Glioma / diagnosis*
  • Optic Nerve Glioma / surgery*
  • Optic Nerve Neoplasms / complications
  • Optic Nerve Neoplasms / diagnosis*
  • Optic Nerve Neoplasms / surgery*
  • Pregnancy
  • Pregnancy Complications
  • Pregnancy Trimester, Third
  • Treatment Outcome
  • Vision Disorders / etiology