Using stem cell oxygen physiology to optimize blastocyst culture while minimizing hypoxic stress

J Assist Reprod Genet. 2017 Oct;34(10):1251-1259. doi: 10.1007/s10815-017-0971-x. Epub 2017 Jun 24.

Abstract

This review is a response to the Fellows Forum on testing 2% oxygen for best culture of human blastocysts (J Ass Reprod Gen 34:303-8, 1; J Ass Reprod Gen 34:309-14, 2) prior to embryo transfer. It is a general analysis in support of the position that an understanding of stem cell physiology and responses to oxygen are necessary for optimization of blastocyst culture in IVF and to enhance reproductive success in fertile women.

Keywords: Blastocyst; Hypoxic stress; IVF; Oxygen optimization; Stem cells.

Publication types

  • Comment

MeSH terms

  • Blastocyst
  • Cell Physiological Phenomena
  • Fellowships and Scholarships
  • Female
  • Humans
  • Infertility*
  • Oxygen*
  • Stem Cells

Substances

  • Oxygen