Morgan's legacy: fruit flies and the functional annotation of conserved genes

Hugo J Bellen; Shinya Yamamoto

doi:10.1016/j.cell.2015.09.009

Morgan's legacy: fruit flies and the functional annotation of conserved genes

Cell. 2015 Sep 24;163(1):12-4. doi: 10.1016/j.cell.2015.09.009.

Authors

Hugo J Bellen¹, Shinya Yamamoto²

Affiliations

¹ Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA; Howard Hughes Medical Institute (HHMI), Houston, TX, 77030, USA. Electronic address: hbellen@bcm.edu.
² Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA; Jan and Dan Duncan Neurological Research Institute, Texas Children's Hospital, Houston, TX 77030, USA.

Abstract

In 1915, "The Mechanism of Mendelian Heredity" was published by four prominent Drosophila geneticists. They discovered that genes form linkage groups on chromosomes inherited in a Mendelian fashion and laid the genetic foundation that promoted Drosophila as a model organism. Flies continue to offer great opportunities, including studies in the field of functional genomics.

Publication types

Historical Article

MeSH terms

Animals
Drosophila melanogaster / genetics*
Genetic Techniques
Genetics / history*
History, 20th Century
Humans
Models, Animal

Abstract

Publication types

MeSH terms

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