Dietary delivery: a new avenue for microRNA therapeutics?

Kendal D Hirschi; Gail J Pruss; Vicki Vance

doi:10.1016/j.tibtech.2015.06.003

Dietary delivery: a new avenue for microRNA therapeutics?

Trends Biotechnol. 2015 Aug;33(8):431-2. doi: 10.1016/j.tibtech.2015.06.003. Epub 2015 Jun 22.

Authors

Kendal D Hirschi¹, Gail J Pruss², Vicki Vance²

Affiliations

¹ United States Department of Agriculture (USDA)/Agricultural Research Service (ARS) Children's Nutrition Research Center, Baylor College of Medicine, 1100 Bates Street, Houston, TX 77030, USA. Electronic address: kendalh@bcm.edu.
² Department of Biological Sciences, University of South Carolina, Columbia, SC 29208, USA.

PMID: 26113189
DOI: 10.1016/j.tibtech.2015.06.003

Abstract

Many people carefully monitor their food choices, adhering to the philosophy that 'you are what you eat'. Recent research adds a new wrinkle to that old adage, suggesting that dietary small RNAs (sRNAs) can control the gene expression of the consumer and may provide an effective, noninvasive, and inexpensive therapy for many human diseases.

Publication types

Review

MeSH terms

Administration, Oral*
Animals
Drug Delivery Systems*
Food
Gene Expression / drug effects*
Humans
MicroRNAs* / administration & dosage
MicroRNAs* / pharmacology
RNA, Small Interfering* / administration & dosage
RNA, Small Interfering* / pharmacology

Substances

MicroRNAs
RNA, Small Interfering

Grants and funding

R03 CA181895/CA/NCI NIH HHS/United States