Trypanosoma cruzi screening in Texas blood donors, 2008-2012

Epidemiol Infect. 2016 Apr;144(5):1010-3. doi: 10.1017/S0950268814002234. Epub 2014 Aug 29.

Abstract

Chagas disease is an important emerging disease in Texas that results in cardiomyopathy in about 30% of those infected with the parasite Trypanosoma cruzi. Between the years 2008 and 2012, about 1/6500 blood donors were T. cruzi antibody-confirmed positive. We found older persons and minority populations, particularly Hispanic, at highest risk for screening positive for T. cruzi antibodies during routine blood donation. Zip code analysis determined that T. cruzi is associated with poverty. Chagas disease has a significant disease burden and is a cause of substantial economic losses in Texas.

Keywords: Blood donors; Chagas disease; RIPA; Trypanosoma cruzi; repeat reactive; risk factors; seroprevalence.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Protozoan / blood
  • Blood Donors / statistics & numerical data*
  • Chagas Disease / epidemiology*
  • Chagas Disease / parasitology
  • Female
  • Humans
  • Male
  • Mass Screening*
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Seroepidemiologic Studies
  • Socioeconomic Factors
  • Texas / epidemiology
  • Trypanosoma cruzi / isolation & purification*
  • Young Adult

Substances

  • Antibodies, Protozoan