Candida speciation, antifungal treatment and adverse events in pediatric invasive candidiasis: results from 441 infections in a prospective, multi-national study

Pediatr Infect Dis J. 2014 Dec;33(12):1294-6. doi: 10.1097/INF.0000000000000431.

Abstract

A multi-national prospective study of pediatric patients with invasive candidiasis between August 2007 and September 2012 was performed and included 441 infections. Variation in infecting Candida species and antifungals used was noted between US and non-US sites. Antifungal-associated adverse events were most common with polyene use.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Antifungal Agents / adverse effects*
  • Antifungal Agents / therapeutic use*
  • Candida / classification*
  • Candida / drug effects*
  • Candida / isolation & purification
  • Candidiasis, Invasive / drug therapy*
  • Candidiasis, Invasive / microbiology*
  • Child
  • Child, Preschool
  • Drug Resistance, Fungal
  • Female
  • Humans
  • Infant
  • Male
  • Prospective Studies
  • Treatment Outcome
  • United States

Substances

  • Antifungal Agents