Changes in Streptococcus pneumoniae serotype 19A invasive infections in children from 1993 to 2011

J Clin Microbiol. 2013 Apr;51(4):1294-7. doi: 10.1128/JCM.00058-13. Epub 2013 Feb 6.

Abstract

Among 594 Streptococcus pneumoniae serotype 19A invasive pneumococcal disease (IPD) isolates collected from 1993 to 2011, we identified 85 sequence types by multilocus sequence typing. CC320 was associated with multidrug resistance and reduced susceptibility to penicillin and ceftriaxone and still predominated among declining serotype 19A IPD isolates following PCV13 introduction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / pharmacology
  • Child
  • Child, Preschool
  • Drug Resistance, Bacterial
  • Female
  • Genotype
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Molecular Epidemiology
  • Multilocus Sequence Typing*
  • Pneumococcal Infections / epidemiology*
  • Pneumococcal Infections / microbiology*
  • Prevalence
  • Serotyping
  • Streptococcus pneumoniae / classification*
  • Streptococcus pneumoniae / drug effects
  • Streptococcus pneumoniae / genetics
  • Streptococcus pneumoniae / isolation & purification*
  • Young Adult

Substances

  • Anti-Bacterial Agents