A 90-year-old woman with orthostatic hypotension and near-syncope was found to have a low-normal level of vitamin B(12) and no other medical findings that could explain her orthostasis. Her symptoms responded to vitamin B(12) replacement therapy. This case shows that vitamin B(12) deficiency can induce orthostatic hypotension and syncope that are correctable by vitamin B(12) replacement.
Keywords: Hypotension, orthostatic/etiology/therapy; vitamin B 12 deficiency; vitamin B 12 replacement; vitamin B 12/therapeutic use.