Preterm premature rupture of membranes: clinical outcomes of late-preterm infants

Clin Pediatr (Phila). 2010 Jan;49(1):60-5. doi: 10.1177/0009922809342460. Epub 2009 Jul 30.

Abstract

Objective: To determine gestational age-specific neonatal outcomes of late preterm infants delivered as a consequence of premature rupture of membranes (PROM).

Methods: Retrospective cohort study of infants born to women delivered electively due to preterm PROM between 34(0/7) and 36(6/7) weeks of gestation. Neonatal outcomes were compared between those delivered at 34(0/7) to 34( 6/7) weeks, at 35(0/7) to 35(6/7) weeks, and at 36( 0/7) to 36(6/7) weeks.

Results: 192 infants were identified. The 34(0/7) to 34(6/7) week infants had significantly higher neonatal intensive care admission rate (72.5%) compared to those at 35( 0/7) to 35(6/7) weeks (22.8%) and at 36 to 36(6/7) weeks (17.8%) (P < .05). Neonatal respiratory distress syndrome was significantly higher at 34(0/7) to 34(6/7) weeks (35.4%) compared with 35(0/7) to 35(6/7) week and 36(0/7) to 36( 6/7) week infants (10.5% and 4.1%; P < .05). The longest hospitalization occurred in the 34(0/7) to 34(6/7) week infants (248.5 +/- 20.0 hours).

Conclusion: Substantial short-term morbidity occurred in late preterm infants. The greatest number of complications affected infants born at 34(0/7) to 34(6/7) weeks.

MeSH terms

  • Analysis of Variance
  • Female
  • Fetal Membranes, Premature Rupture*
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / etiology
  • Infant, Premature*
  • Intensive Care Units, Neonatal / statistics & numerical data
  • Length of Stay / statistics & numerical data
  • Pregnancy
  • Pregnancy Outcome
  • Respiratory Distress Syndrome, Newborn / etiology
  • Retrospective Studies