On-pump versus off-pump coronary artery bypass grafting in a cohort of 63,000 patients

Ann Thorac Surg. 2009 Jun;87(6):1820-6; discussion 1826-7. doi: 10.1016/j.athoracsur.2009.03.052.

Abstract

Background: The best approach to surgical myocardial revascularization remains controversial. We compared outcomes of conventional on-pump coronary artery bypass grafting (CABG) and off-pump coronary artery bypass (OPCAB) by using a nonvoluntary national database.

Methods: In the 2004 Nationwide Inpatient Sample database, we identified 63,047 discharge records of patients who underwent CABG (n = 48,658) or OPCAB (n = 14,389). We analyzed seven preoperative variables, including the Deyo comorbidity index and five outcome measures. Multivariable logistic regression was used to identify independent predictors of outcomes.

Results: CABG and OPCAB patients had similar demographics and comorbidities. They also had similar rates of in-hospital mortality (3.0% vs 3.2%; p = 0.14) and postoperative stroke (1.8% vs 1.7%; p = 0.53). However, OPCAB patients had longer hospital stays (10.2 +/- 9.4 vs 9.9 +/- 8.5 days; p < 0.0001) and higher hospital costs ($38,793 +/- $30,830 vs $37,806 +/- $28,705; p = 0.0005) than CABG patients. Multivariable regression analysis showed that OPCAB independently predicted 0.6 more days of hospital stay (95% confidence interval [CI], 0.4 to 0.8 day; R(2) = 0.09; p < 0.0001) and $1,497 more in hospital costs (95% CI, $779 to $2,216; R(2) = 0.09; p < 0.01) per patient.

Conclusions: OPCAB does not produce lower postoperative mortality or stroke rates than CABG. Furthermore, OPCAB is associated with longer hospital stays and higher hospital costs.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Coronary Artery Bypass / methods*
  • Coronary Artery Bypass, Off-Pump
  • Female
  • Humans
  • Male
  • Treatment Outcome