Basidiomycetous fungal Inonotus tropicalis sacral osteomyelitis in X-linked chronic granulomatous disease

Pediatr Infect Dis J. 2007 Jul;26(7):655-6. doi: 10.1097/INF.0b013e3180616cd0.

Abstract

Osteomyelitis is a common clinical manifestation of chronic granulomatous disease, a disorder of phagocytic function. Fungal organisms account for a significant proportion of these infections. We describe the clinical presentation and subsequent destructive sacral osteomyelitis with a basidiomycetous mold, Inonotus tropicalis, in a patient with an X-linked chronic granulomatous disease.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Basidiomycota / isolation & purification*
  • Caspofungin
  • Echinocandins
  • Granulomatous Disease, Chronic / complications*
  • HMGB1 Protein / therapeutic use
  • Humans
  • Lipopeptides
  • Male
  • Mycoses / drug therapy*
  • Mycoses / microbiology*
  • Osteomyelitis / microbiology*
  • Peptides, Cyclic / therapeutic use
  • Pyrimidines / therapeutic use
  • Sacrum / microbiology
  • Sacrum / pathology
  • Triazoles / therapeutic use
  • Voriconazole

Substances

  • Antifungal Agents
  • Echinocandins
  • HMGB1 Protein
  • Lipopeptides
  • Peptides, Cyclic
  • Pyrimidines
  • Triazoles
  • Caspofungin
  • Voriconazole