Abstract
We describe a case of insidious small bone osteomyelitis and soft tissue abscess with Burkholderia gladioli in a 6-year-old Caucasian boy with chronic granulomatous disease. DNA sequencing of the 16S ribosomal RNA gene confirmed the bacterial identification. Clinical cure was achieved with a combination of antimicrobial therapy and surgical debridement. A review of infections caused by Burkholderia spp., other than Burkholderia cepacia complex, in pediatric patients with chronic granulomatous disease is provided.
MeSH terms
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Anti-Bacterial Agents / therapeutic use
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Burkholderia Infections / complications
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Burkholderia Infections / diagnosis*
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Burkholderia Infections / drug therapy
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Burkholderia gladioli / isolation & purification*
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Child
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Follow-Up Studies
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Granulomatous Disease, Chronic / complications
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Granulomatous Disease, Chronic / diagnosis*
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Granulomatous Disease, Chronic / genetics
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Humans
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Male
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Osteomyelitis / complications*
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Osteomyelitis / diagnosis*
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Osteomyelitis / drug therapy
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RNA, Ribosomal, 16S / analysis
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RNA, Ribosomal, 16S / genetics
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Risk Assessment
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Severity of Illness Index
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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RNA, Ribosomal, 16S