Clonality of Streptococcus pneumoniae serotype 1 isolates from pediatric patients in the United States

J Clin Microbiol. 2004 Jun;42(6):2810-2. doi: 10.1128/JCM.42.6.2810-2812.2004.

Abstract

We compared Streptococcus pneumoniae serotype 1 isolates causing disease among children in six geographic regions of the United States to determine genetic relatedness. Genomic fingerprints were determined by repetitive element polymorphism PCR (Rep-PCR). Multilocus sequence type characterization was performed on selected isolates. Four different genomic banding patterns were identified by Rep-PCR. One profile (clone 1) was predominant and matched sequence type 227.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Humans
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Serotyping
  • Streptococcus pneumoniae / classification
  • Streptococcus pneumoniae / genetics*
  • United States