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2012 27
2013 220
2014 203
2015 1
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469 results

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The following term was not found in PubMed: elife.38550.001
Page 1
RNA-programmed genome editing in human cells.
Jinek M, East A, Cheng A, Lin S, Ma E, Doudna J. Jinek M, et al. Elife. 2013 Jan 29;2:e00471. doi: 10.7554/eLife.00471. Elife. 2013. PMID: 23386978 Free PMC article.
These results show that RNA-programmed genome editing is a facile strategy for introducing site-specific genetic changes in human cells.DOI:http://dx.doi.org/10.7554/eLife.00471.001....
These results show that RNA-programmed genome editing is a facile strategy for introducing site-specific genetic changes in human cells.DOI: …
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis.
Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, Thomas AG, Gleason CE, Tatonetti NP, Slusher BS, Stockwell BR. Dixon SJ, et al. Elife. 2014 May 20;3:e02523. doi: 10.7554/eLife.02523. Elife. 2014. PMID: 24844246 Free PMC article.
Finally, using a genetic approach, we identified new genes dramatically upregulated in cells resistant to ferroptosis.DOI: http://dx.doi.org/10.7554/eLife.02523.001....
Finally, using a genetic approach, we identified new genes dramatically upregulated in cells resistant to ferroptosis.DOI: http://dx.doi.org …
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus.
Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, Huang Y, Qi Y, Peng B, Wang H, Fu L, Song M, Chen P, Gao W, Ren B, Sun Y, Cai T, Feng X, Sui J, Li W. Yan H, et al. Elife. 2012 Nov 13;1:e00049. doi: 10.7554/eLife.00049. Elife. 2012. PMID: 23150796 Free PMC article.
Our results demonstrate that NTCP is a functional receptor for HBV and HDV.DOI:http://dx.doi.org/10.7554/eLife.00049.001....
Our results demonstrate that NTCP is a functional receptor for HBV and HDV.DOI:http://dx.doi.org/10.7554/eLife.00049.001....
Epigenetic transcriptional memory.
D'Urso A, Brickner JH. D'Urso A, et al. Curr Genet. 2017 Jun;63(3):435-439. doi: 10.1007/s00294-016-0661-8. Epub 2016 Nov 2. Curr Genet. 2017. PMID: 27807647 Free PMC article. Review.
Epigenetic transcriptional memory in response to a previous stimulus can produce heritable changes in the response of an organism to the same stimulus, quantitatively or qualitatively altering changes in gene expression (Brickner et al. in PLoS Biol, 5:e81, 2007; Light et al. in …
Epigenetic transcriptional memory in response to a previous stimulus can produce heritable changes in the response of an organism to the sam …
Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis.
Scher JU, Sczesnak A, Longman RS, Segata N, Ubeda C, Bielski C, Rostron T, Cerundolo V, Pamer EG, Abramson SB, Huttenhower C, Littman DR. Scher JU, et al. Elife. 2013 Nov 5;2:e01202. doi: 10.7554/eLife.01202. Elife. 2013. PMID: 24192039 Free PMC article.
This work identifies a potential role for P. copri in the pathogenesis of RA. DOI: http://dx.doi.org/10.7554/eLife.01202.001....
This work identifies a potential role for P. copri in the pathogenesis of RA. DOI: http://dx.doi.org/10.7554/eLife.01202.001.. …
Are the Breaks Breaking Down?
Ewell LA. Ewell LA. Epilepsy Curr. 2019 Mar-Apr;19(2):117-118. doi: 10.1177/1535759719835350. Epilepsy Curr. 2019. PMID: 30955417 Free PMC article.
Altered Hippocampal Interneuron Activity Precedes Ictal Onset Miri ML, Vinck M, Pant R, Cardin JA. Elife. 2018;7. pii: e40750. doi:10.7554/eLife.40750. Although failure of GABAergic inhibition is a commonly hypothesized mechanism underlying seizure disorders, the se …
Altered Hippocampal Interneuron Activity Precedes Ictal Onset Miri ML, Vinck M, Pant R, Cardin JA. Elife. 2018;7. pii: e40750. doi:10
Distinct glycerophospholipids potentiate Gsα-activated adenylyl cyclase activity.
Seth A, Landau M, Shevchenko A, Traikov S, Schultz A, Elsabbagh S, Schultz JE. Seth A, et al. Cell Signal. 2022 Sep;97:110396. doi: 10.1016/j.cellsig.2022.110396. Epub 2022 Jul 2. Cell Signal. 2022. PMID: 35787445 Free article.
Previously we proposed that these membrane domains are orphan receptors (https://doi.org/10.7554/eLife.13098; https://doi.org/10.1016/j.cellsig.2020.109538). ...
Previously we proposed that these membrane domains are orphan receptors (https://doi.org/10.7554/eLife.13098; https://doi.org/ …
Improved Macrophage Enrichment from Mouse Skeletal Muscle.
Krasniewski LK, Tsitsipatis D, Izydore EK, Shi C, Piao Y, Michel M, Sen P, Gorospe M, Cui CY. Krasniewski LK, et al. Bio Protoc. 2022 Dec 5;12(23):e4561. doi: 10.21769/BioProtoc.4561. eCollection 2022 Dec 5. Bio Protoc. 2022. PMID: 36561115 Free PMC article.
This method has allowed the isolation of CD45 (+) /CD11b (+) macrophage-enriched cells from young and old mice, which can be further used for flow cytometric analysis, fluorescence-activated cell sorting (FACS), and single-cell RNA sequencing. This protocol was validated in: eLif …
This method has allowed the isolation of CD45 (+) /CD11b (+) macrophage-enriched cells from young and old mice, which can be further used fo …
Synchronous and asynchronous modes of synaptic transmission utilize different calcium sources.
Wen H, Hubbard JM, Rakela B, Linhoff MW, Mandel G, Brehm P. Wen H, et al. Elife. 2013 Dec 24;2:e01206. doi: 10.7554/eLife.01206. Elife. 2013. PMID: 24368731 Free PMC article.
The neuromuscular junction and CNS neurons share these features, raising the possibility that secondary calcium sources are common among synapses with prominent asynchronous release. DOI: http://dx.doi.org/10.7554/eLife.01206.001....
The neuromuscular junction and CNS neurons share these features, raising the possibility that secondary calcium sources are common among syn …
Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2.
Nocka LM, Eisen TJ, Iavarone AT, Groves JT, Kuriyan J. Nocka LM, et al. Elife. 2023 Apr 26;12:e82676. doi: 10.7554/eLife.82676. Elife. 2023. PMID: 37159508 Free PMC article.
We showed previously that Btk is activated by PH-TH dimerization, which is triggered on membranes by the phosphatidyl inositol phosphate PIP(3), or in solution by inositol hexakisphosphate (IP(6)) (Wang et al., 2015, https://doi.org/10.7554/eLife.06074). We now repo …
We showed previously that Btk is activated by PH-TH dimerization, which is triggered on membranes by the phosphatidyl inositol phosphate PIP …
469 results