HIV Infection-Associated Frailty: The Solution for Now Is Antiretroviral Drugs: A Perspective

J Int Assoc Provid AIDS Care. 2019 Jan-Dec:18:2325958219831045. doi: 10.1177/2325958219831045.

Authors

Stephen A Klotz¹, Nicole Bradley², Shannon Smith¹, Nafees Ahmad²

Affiliations

¹ 1 Division of Infectious Diseases, Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ, USA.
² 2 Department of Immunobiology, College of Medicine, University of Arizona, Tucson, AZ, USA.

Abstract

This Perspective article provides a new view of frailty as it relates to HIV-1 infection. We discuss new findings and where our research is going.

Keywords: CD4 count and CD8 T cells; HIV-1 infection; antiretroviral drugs; frailty; immune function recovery.

MeSH terms

Aging*
Anti-Retroviral Agents / therapeutic use*
Antiretroviral Therapy, Highly Active
CD4 Lymphocyte Count
CD8-Positive T-Lymphocytes / immunology
Frailty / virology*
HIV Infections / complications*
HIV Infections / drug therapy*
Humans
Viral Load / drug effects

Substances

Anti-Retroviral Agents