Human Norovirus Propagation in Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells

Shintaro Sato; Kota Hisaie; Shiho Kurokawa; Akio Suzuki; Naomi Sakon; Yohei Uchida; Yoshikazu Yuki; Hiroshi Kiyono

doi:10.1016/j.jcmgh.2018.11.001

Human Norovirus Propagation in Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells

Cell Mol Gastroenterol Hepatol. 2019;7(3):686-688.e5. doi: 10.1016/j.jcmgh.2018.11.001. Epub 2018 Dec 10.

Authors

Shintaro Sato¹, Kota Hisaie², Shiho Kurokawa³, Akio Suzuki⁴, Naomi Sakon⁵, Yohei Uchida³, Yoshikazu Yuki³, Hiroshi Kiyono⁶

Affiliations

¹ Mucosal Vaccine Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan; Mucosal Vaccine Project, BIKEN Center for Innovative Vaccine Research and Development, Research Foundation for Microbial Diseases, Osaka University, Osaka, Japan; Graduate School of Medicine, Osaka University, Osaka, Japan; Division of Mucosal Vaccine, Research and Development Center for Mucosal Vaccines, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Division of Mucosal Barriology, Research and Development Center for Mucosal Vaccines, Institute of Medical Science, The University of Tokyo, Tokyo, Japan. Electronic address: shinta@biken.osaka-u.ac.jp.
² Mucosal Vaccine Project, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan; Graduate School of Medicine, Osaka University, Osaka, Japan.
³ Division of Mucosal Vaccine, Research and Development Center for Mucosal Vaccines, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
⁴ Mucosal Vaccine Project, BIKEN Center for Innovative Vaccine Research and Development, Research Foundation for Microbial Diseases, Osaka University, Osaka, Japan.
⁵ Department of Microbiology, Osaka Institute of Public Health, Osaka, Japan.
⁶ Division of Mucosal Vaccine, Research and Development Center for Mucosal Vaccines, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Division of Mucosal Barriology, Research and Development Center for Mucosal Vaccines, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Division of Mucosal Immunology, IMSUT Distinguished Professor Unit, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Department of Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan; Department of Medicine, School of Medicine and CU-UCSD Center for Mucosal Immunology, Allergy and Vaccine, University of California, San Diego, San Diego, California.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies / pharmacology
Cell Line
Cell Polarity / drug effects
Epithelial Cells / drug effects
Epithelial Cells / virology*
Humans
Induced Pluripotent Stem Cells / cytology*
Induced Pluripotent Stem Cells / drug effects
Intestines / cytology*
Norovirus / drug effects
Norovirus / genetics
Norovirus / growth & development*
Sodium Hypochlorite / pharmacology
Virion / drug effects
Virion / metabolism
Virus Inactivation / drug effects
Virus Replication / drug effects

Substances

Antibodies
Sodium Hypochlorite