Abstract
Cortisol-secreting adrenal tumors are responsible for 10% to 15% of all cases of naturally occurring canine hyperadrenocorticism. Differentiation of adrenal-dependent hyperadrenocorticism from pituitary-dependent hyperadrenocorticism is very important because the recommended therapeutic approaches for each are different, and the prognosis also may be different. A stepwise approach to diagnosing and staging the disease is needed. Treatment options include surgery and administration of mitotane or ketoconazole.
MeSH terms
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Adenoma / diagnosis
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Adenoma / therapy
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Adenoma / veterinary*
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Adrenal Gland Neoplasms / diagnosis
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Adrenal Gland Neoplasms / therapy
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Adrenal Gland Neoplasms / veterinary*
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Adrenal Glands / drug effects
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Adrenal Glands / surgery
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Adrenocorticotropic Hormone / blood
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Animals
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Antifungal Agents / therapeutic use
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Antineoplastic Agents / therapeutic use
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Dog Diseases / diagnosis*
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Dog Diseases / metabolism
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Dog Diseases / therapy*
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Dogs
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Hydrocortisone / blood
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Hydrocortisone / metabolism*
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Ketoconazole / therapeutic use
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Mitotane / therapeutic use
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Prognosis
Substances
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Antifungal Agents
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Antineoplastic Agents
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Mitotane
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Adrenocorticotropic Hormone
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Ketoconazole
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Hydrocortisone