Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk

Yarden Golan; Mary Prahl; Arianna Cassidy; Christine Y Lin; Nadav Ahituv; Valerie J Flaherman; Stephanie L Gaw

doi:10.1001/jamapediatrics.2021.1929

Evaluation of Messenger RNA From COVID-19 BTN162b2 and mRNA-1273 Vaccines in Human Milk

JAMA Pediatr. 2021 Oct 1;175(10):1069-1071. doi: 10.1001/jamapediatrics.2021.1929.

Authors

Yarden Golan^{1

2}, Mary Prahl³, Arianna Cassidy⁴, Christine Y Lin⁴, Nadav Ahituv^{1

2}, Valerie J Flaherman³, Stephanie L Gaw⁴

Affiliations

¹ Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco.
² Institute for Human Genetics, University of California, San Francisco.
³ Department of Pediatrics, University of California, San Francisco.
⁴ Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco.

Abstract

This cohort study analyzes milk samples from lactating mothers to determine if COVID-19 vaccine–related messenger RNA was detectable in human milk after vaccination.

MeSH terms

2019-nCoV Vaccine mRNA-1273
Adult
BNT162 Vaccine
COVID-19 / prevention & control
COVID-19 Vaccines / pharmacology*
Female
Humans
Milk, Human / metabolism*
Milk, Human / virology*
RNA, Messenger / metabolism*
RNA, Viral / metabolism*
SARS-CoV-2 / genetics
SARS-CoV-2 / isolation & purification
Time Factors
Young Adult

Substances

COVID-19 Vaccines
RNA, Messenger
RNA, Viral
2019-nCoV Vaccine mRNA-1273
BNT162 Vaccine

Grants and funding

K23 AI127886/AI/NIAID NIH HHS/United States