Regulation of BMP2K in AP2M1-mediated EGFR internalization during the development of gallbladder cancer

Xiaoling Song; Maolan Li; Wenguang Wu; Wei Dang; Yuan Gao; Rui Bian; Runfa Bao; Yunping Hu; Defei Hong; Jun Gu; Yingbin Liu

doi:10.1038/s41392-020-00250-3

Regulation of BMP2K in AP2M1-mediated EGFR internalization during the development of gallbladder cancer

Signal Transduct Target Ther. 2020 Aug 13;5(1):154. doi: 10.1038/s41392-020-00250-3.

Authors

Xiaoling Song^#^{1

2

3}, Maolan Li^#^{1

2}, Wenguang Wu^#^{2

4}, Wei Dang^#^{1

2

3}, Yuan Gao^{2

3

4}, Rui Bian^{2

3

4}, Runfa Bao^{1

2}, Yunping Hu^{1

2

3}, Defei Hong⁵, Jun Gu^{6

7}, Yingbin Liu^{8

9

10

11}

Affiliations

¹ Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, 200092, Shanghai, China.
² Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai Jiao Tong University, 200127, Shanghai, China.
³ State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University, 160 Pujian Road, 200127, Shanghai, China.
⁴ Department of Biliary-Pancreatic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, 200127, Shanghai, China.
⁵ Department of General Surgery, Sir Run Run Shaw Hospital, The Medicine School of Zhejiang University, East Qinchun Road, 310020, Hangzhou, Zhejiang Province, China. hongdefi@163.com.
⁶ Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, 200092, Shanghai, China. gujun02@xinhuamed.com.cn.
⁷ Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai Jiao Tong University, 200127, Shanghai, China. gujun02@xinhuamed.com.cn.
⁸ Department of General Surgery and Laboratory of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, 200092, Shanghai, China. laoniulyb@shsmu.edu.cn.
⁹ Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai Jiao Tong University, 200127, Shanghai, China. laoniulyb@shsmu.edu.cn.
¹⁰ State Key Laboratory of Oncogenes and Related Genes, Shanghai Jiao Tong University, 160 Pujian Road, 200127, Shanghai, China. laoniulyb@shsmu.edu.cn.
¹¹ Department of Biliary-Pancreatic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 160 Pujian Road, 200127, Shanghai, China. laoniulyb@shsmu.edu.cn.

^# Contributed equally.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adaptor Proteins, Vesicular Transport / genetics*
Cell Proliferation
Disease-Free Survival
ErbB Receptors / economics
ErbB Receptors / genetics
Female
Gallbladder Neoplasms / genetics*
Gallbladder Neoplasms / pathology
Gene Expression Regulation, Neoplastic / genetics
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Protein Serine-Threonine Kinases / genetics*

Substances

AP2M1 protein, human
Adaptor Proteins, Vesicular Transport
EGFR protein, human
ErbB Receptors
BMP2K protein, human
Protein Serine-Threonine Kinases