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Architecture of the human interactome defines protein communities and disease networks.
Nature. 2017 May 25;545(7655):505-509. doi: 10.1038/nature22366. Epub 2017 May 17.
Nature. 2017.
PMID: 28514442
Free PMC article.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.
Chen S, Fragoza R, Klei L, Liu Y, Wang J, Roeder K, Devlin B, Yu H.
Chen S, et al.
Nat Genet. 2018 Jul;50(7):1032-1040. doi: 10.1038/s41588-018-0130-z. Epub 2018 Jun 11.
Nat Genet. 2018.
PMID: 29892012
Free PMC article.
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Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.
Fragoza R, Das J, Wierbowski SD, Liang J, Tran TN, Liang S, Beltran JF, Rivera-Erick CA, Ye K, Wang TY, Yao L, Mort M, Stenson PD, Cooper DN, Wei X, Keinan A, Schimenti JC, Clark AG, Yu H.
Fragoza R, et al.
Nat Commun. 2019 Sep 12;10(1):4141. doi: 10.1038/s41467-019-11959-3.
Nat Commun. 2019.
PMID: 31515488
Free PMC article.
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ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer.
Tsunoda T, Riku M, Yamada N, Tsuchiya H, Tomita T, Suzuki M, Kizuki M, Inoko A, Ito H, Murotani K, Murakami H, Saeki Y, Kasai K.
Tsunoda T, et al.
EMBO Rep. 2022 Feb 3;23(2):e51182. doi: 10.15252/embr.202051182. Epub 2021 Dec 20.
EMBO Rep. 2022.
PMID: 34927784
Free PMC article.
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