The rate of drug overdose deaths involving heroin increased slightly during 2006-2010 but more than tripled during 2010-2015 for all age groups shown. During 2010-2015, the rates increased from 1.2 to 3.8 per 100,000 for persons aged 15-24 years, from 2.2 to 9.7 for persons aged 25-34 years, from 1.6 to 7.4 for persons aged 35-44 years, from 1.4 to 5.6 for persons aged 45-54 years, and from 0.7 to 3.4 for persons aged 55-64 years. In 2015, the rate of drug overdose deaths involving heroin was highest for persons aged 25-34.