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2012 | 1 |
2018 | 1 |
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MDA5 assembles into a polar helical filament on dsRNA.
Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18437-41. doi: 10.1073/pnas.1212186109. Epub 2012 Oct 22.
Proc Natl Acad Sci U S A. 2012.
PMID: 23090998
Free PMC article.
Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Yu Q, Qu K, Modis Y.
Yu Q, et al.
Mol Cell. 2018 Dec 20;72(6):999-1012.e6. doi: 10.1016/j.molcel.2018.10.012. Epub 2018 Nov 15.
Mol Cell. 2018.
PMID: 30449722
Free PMC article.
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ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity.
Liu G, Lee JH, Parker ZM, Acharya D, Chiang JJ, van Gent M, Riedl W, Davis-Gardner ME, Wies E, Chiang C, Gack MU.
Liu G, et al.
Nat Microbiol. 2021 Apr;6(4):467-478. doi: 10.1038/s41564-021-00884-1. Epub 2021 Mar 16.
Nat Microbiol. 2021.
PMID: 33727702
Free PMC article.
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